10% CALCIUM GLUCONATE Injection
Calcium Gluconate
100mg/ml
Pharmaceutical Solution Industries Ltd.
| Pack size | 10ml Plastic Ampoule x 50 (5's Strip x 10) |
|---|---|
| Dispensing mode | POM |
| Source | SAUDI ARABIA |
| Agent | GULF DRUG EST. |
| Retail Price | 162.00 AED |
Available as:
Indications
10% CALCIUM GLUCONATE Injection is used for:
Postmenopausal osteoporosis, Osteoporosis, Hypoparathyroidism, Latent tetany, Rickets, Osteomalacia, Hyperkalemia, Hypocalcemia, Magnesium sulfate overdose
Adult Dose
Hypocalcemia
Treatment of conditions arising from calcium deficiency (eg, hypocalcemic tetany, hypoparathyroidism)
Mild (ionized calcium 1-1.2 mmol/L)
Management of non-life-threatening symptoms
IV: 1-2 g over 2 hours
Severe (ionized calcium <1 mmol/L)
Without seizure or tetany: 0.5 mg/kg/hr IV; may be increased to 2 mg/kg/hr; not to exceed 3-4 g IV over 4 hours
Hypocalcemic tetany: 100-300 mg elemental calcium (~3 g calcium gluconate) IV over 5-10 minutes, followed by continuous IV infusion at 0.5 mg/kg/hr (may be increased to 2 mg/kg/hr)
Monitor serum calcium q4-6hr to maintain serum calcium levels
Child Dose
Hypocalcemia
Treatment of conditions arising from calcium deficiency (eg, hypocalcemic tetany, hypoparathyroidism)
Severe
Neonates: 200-800 mg/kg/day IV by continuous infusion or divided q6hr as intermittent infusions
Infants/children: 200-500 mg/kg/day IV by continuous infusion or divided q6hr as intermittent infusions
Hypocalcemic tetany
100-200 mg/kg IV over 10 minutes; may be repeated after 6 hours, or initiate continuous infusion not to exceed 500 mg/kg/day
Renal Dose
Administration
Contra Indications
Patients with calcium renal calculi or history of renal calculi. Conditions associated with hypercalcaemia and hypercalciuria.
Precautions
Impaired renal function; cardiac disease; hypercalcaemia-associated diseases, e.g. sarcoidosis; other malignancies. Pregnancy.
Lactation: Calcium enters human milk; use with caution
Pregnancy-Lactation
Pregnancy category: C
Lactation: Calcium enters human milk; use with caution
Interactions
Calcium Gluconate: Co-admin of high calcium doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. May potentiate digoxin toxicity. Decreases effects of calcium-channel blockers. Enhanced absorption with calcitriol (a vitamin D metabolite).
Adverse Effects
Side effects of Calcium Gluconate :
Bradycardia, Hypotension, Headache, Constipation, Diarrhea, Flatulence, Nausea, Vomiting, Hypomagnesemia, Hypophosphatemia, Extravasation necrosis
Hypercalcaemia characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi; chalky taste, hot flushes and peripheral vasodilation.
Potentially Fatal: Cardiac arrhythmias and coma.
Mechanism of Action
Calcium gluconate/lactate is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.
Note
10% CALCIUM GLUCONATE 100mg/ml Injection manufactured by Pharmaceutical Solution Industries Ltd.. Its generic name is Calcium Gluconate. 10% CALCIUM GLUCONATE is availble in United Arab Emirates.
Farmaco UAE drug index information on 10% CALCIUM GLUCONATE Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.