Acular Ls 0.4% Ophthalmic Solution Eye Drops (Solution)
Ketorolac trometamol
4mg/ml
ALLERGAN PHARMACEUTICALS, INC.
| Pack size | 5ml Dropper Bottle |
|---|---|
| Dispensing mode | POM |
| Source | USA |
| Agent | AL BAKER TRADING EST. |
| Retail Price | 19.00 AED |
Indications
Acular Ls 0.4% Ophthalmic Solution Eye Drops (Solution) is used for:
For the short-term (<5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ketorolac trometamol :
Mechanism of Action
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) chemically related to indomethacin and tolmetin. Ketorolac tromethamine is a racemic mixture of [-]S- and [+]R-enantiomeric forms, with the S-form having analgesic activity. Its antiinflammatory effects are believed to be due to inhibition of both cylooxygenase-1 (COX-1) and cylooxygenase-2 (COX-2) which leads to the inhibition of prostaglandin synthesis leading to decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. The resultant reduction in prostaglandin synthesis and activity may be at least partially responsible for many of the adverse, as well as the therapeutic, effects of these medications. Analgesia is probably produced via a peripheral action in which blockade of pain impulse generation results from decreased prostaglandin activity. However, inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation may also contribute to the analgesic effect. In terms of the ophthalmic applications of ketorolac - ocular administration of ketorolac reduces prostaglandin E2 levels in aqueous humor, secondary to inhibition of prostaglandin biosynthesis.
Note
Acular Ls 0.4% Ophthalmic Solution 4mg/ml Eye Drops (Solution) manufactured by ALLERGAN PHARMACEUTICALS, INC.. Its generic name is Ketorolac trometamol. Acular Ls 0.4% Ophthalmic Solution is availble in United Arab Emirates.
Farmaco UAE drug index information on Acular Ls 0.4% Ophthalmic Solution Eye Drops (Solution) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.