Addi-K Tablets

Potassium Chloride
750mg
Leo Pharmaceutical Co.
Pack size 100's
Dispensing mode POM
Source DENMARK
AgentPHARMATRADE
Retail Price 7.00 AED

Indications

Addi-K Tablets is used for: Hypokalemia, Electrolyte replenisher

Adult Dose

Oral Prophylaxis of hypokalaemia and mild K deficiency; Hypokalaemia Adult: Prevention of hypokalaemia: 20 mEq daily. Treatment of hypokalaemia 40-100 mEq/day bid-qid. Give in divided doses if >20 mEq/day. Intravenous Severe acute hypokalaemia Adult: If serum potassium level >2.5 mEq/L, give at a rate not exceeding 10 mEq/hr in a concentration of up to 40 mEq/L. Max dose: 200 mEq/24 hr. If serum potassium level <2 mEq/L, may infuse at a rate of up to 40 mEq/hr. Continuous cardiac monitoring is essential. Max dose: 400 mEq/24 hr. Max Dosage: 2-3 mmol potassium/kg body wt in 24 hrs.

Child Dose

Hypokalemia 0.5-2 mEq/kg PO q12hr Monitor closely: 0.5 mEq/kg/hr IV for 1-2 hr

Renal Dose

Administration

Should be taken with food.

Contra Indications

Hyperchloraemia, severe renal or adrenal insufficiency.

Precautions

Renal or adrenocortical insufficiency; cardiac disease; acute dehydration; extensive tissue destruction. Pregnancy. Ensure adequate urine output; monitor plasma-potassium and other electrolyte concentrations. Discontinue treatment if severe nausea, vomiting or abdominal distress develops. Accumulation of potassium may occur in renal impairment.

Pregnancy-Lactation

Pregnancy There are no human data related to use of potassium chloride extended-release capsules during pregnancy; animal reproductive studies not conducted; potassium supplementation that does not lead to hyperkalemia is not expected to cause fetal harm Lactation Normal potassium ion content of human milk is about 13 mEq per liter; since oral potassium becomes part of the body potassium pool, as long as body potassium is not excessive, contribution of potassium chloride supplementation should have little or no effect on level in human milk

Interactions

Potassium-sparing diuretics, ACE inhibitors, ciclosporin and potassium-containing drugs. Antimuscarinics delay gastric emptying time consequently increasing risk of GI adverse effects esp of solid oral dosage forms.

Adverse Effects

Side effects of Potassium Chloride : GI ulceration (sometimes with haemorrhage and perforation or with late formation of strictures) following the use of enteric-coated K chloride preparation; hyperkalaemia. Oral: Nausea, vomiting, diarrhoea and abdominal cramps. IV: Pain or phloebitis; cardiac toxicity.

Mechanism of Action

Potassium chloride is a major cation of the intracellular fluid. It plays an active role in the conduction of nerve impulses in the heart, brain and skeletal muscle; contraction of cardiac skeletal and smooth muscles; maintenance of normal renal function, acid-base balance, carbohydrate metabolism and gastric secretion.

Note

Addi-K 750mg Tablets manufactured by Leo Pharmaceutical Co.. Its generic name is Potassium Chloride. Addi-K is availble in United Arab Emirates. Farmaco UAE drug index information on Addi-K Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Potassium Chloride :

Tablets
K-CONTIN CONTINUS 600mg
BARD PHARMACEUTICALS (NAPP LAB.UK)
Infusion
POTASSIUM CHLORIDE 15% w/v (Gulf Inject) 150mg/ml
Gulf Inject LLC
Infusion
POTASSIUM CHLORIDE CONCENTRATE 15% w/v 150mg/ml
B.BRAUN MELSUNGEN AG
Infusion
POTASSIUM CHLORIDE S.A.L.F. 1.49g/10ml
S.A.L.F. LABORATORIO FARMACOLOGICO S.p.A