AIMOVIG Solution for Injection in Pre-filled Pen

Erenumab
140 mg/ml
Novartis Pharma AG
Pack size 1 Pre-filled Pen (1 ml)
Dispensing mode POM
Source SWITZERLAND
AgentModern Pharmaceutical Co.
Retail Price 2244.00 AED

Indications

AIMOVIG Solution for Injection in Pre-filled Pen is used for: Migraine Prophylaxis

Adult Dose

Migraine Prophylaxis Indicated for preventive treatment of migraines 70 mg SC once monthly Some patients may need 140 mg SC once monthly (administered as 2 consecutive 70-mg SC doses)

Child Dose

Renal Dose

Renal impairment Mild-to-moderate: Clinical studies did not reveal a difference in pharmacokinetics Severe (eGFR <30 mL/min/1.73 m²): Not studied

Administration

Contra Indications

Hypersensitivity to drug or excipients

Precautions

Hypersensitivity reactions (eg, rash, angioedema, anaphylaxis) reported; may occur within hours or one week following administration; discontinue administration and initiate appropriate therapy if serious reaction occurs

Pregnancy-Lactation

Pregnancy Data are not available regarding fetal risk if used in pregnant women Animal studies No adverse effects on offspring were observed when pregnant monkeys were administered erenumab-aooe throughout gestation Clinical considerations Data suggest that women with migraine may be at increased risk of preeclampsia during pregnancy Lactation Data are not available on the presence in human milk, the effects on the breastfed infant, or the effects on milk production Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition

Interactions

Adverse Effects

Side effects of Erenumab : 1-10% Injection site pain (5-6%) Constipation (1-3%) Cramps, muscle spasms (<3%)

Mechanism of Action

Human monoclonal antibody; binds to the calcitonin gene-related peptide (CGRP) receptor, which is thought to be causally involved in migraine pathophysiology

Note

AIMOVIG 140 mg/ml Solution for Injection in Pre-filled Pen manufactured by Novartis Pharma AG. Its generic name is Erenumab. AIMOVIG is availble in United Arab Emirates. Farmaco UAE drug index information on AIMOVIG Solution for Injection in Pre-filled Pen is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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