Androgel Gel
Testosterone 1% Topical
50mg
SOLVAY PHARMACEUTICALS GmbH
| Pack size | 30 Sachets |
|---|---|
| Dispensing mode | POM-R (Dispense maximum for one month) |
| Source | GERMANY |
| Agent | ALPHAMED CO. (AUH) LTD. |
| Retail Price | 245.00 AED |
Indications
Androgel Gel is used for:
Hypogonadism, Testosterone replacement therapy
Adult Dose
Topical
Adult: Testosterone gels: 50 mg/day initially, applied topically to shoulders, upper arms, or abdomen (not to genitals) each morning; titrated according to predose serum testosterone levels (25 mg/2.5 g, 50 mg/5 g); not to exceed 100 mg/day
Child Dose
Safety and efficacy not established
Renal Dose
Administration
Applying the gel to skin of lower abdomen, inner thighs or shoulders and upper arms, usually once daily.
Contra Indications
Hypercalcaemia or hypercalciuria, males with breast or prostate carcinoma. Pregnancy and lactation.
Precautions
Cardiovascular disorders, skeletal metastases, renal or hepatic impairment, epilepsy, migraine, diabetes or other conditions which may be aggravated by fluid retention, eg heart failure. Elderly, prepubertal boys. Monitor signs of virilization (females) and development of priapism or excessive sexual stimulation (males). Periodic haemoglobin, lipid determinations and rectal prostate examination.
Lactation: Drug is excreted into breast milk; use is contraindicated
Pregnancy-Lactation
Pregnancy category: X
Lactation: Drug is excreted into breast milk; use is contraindicated
Interactions
Enhance activities of ciclosporine, antidiabetics, thyroxine, anticoagulants. Long term use of testosterone may cause resistance to effects of neuromuscular blockers. Enhance fluid retention from corticosteroids.
Adverse Effects
Side effects of Testosterone 1% Topical :
>10%
Pruritus at application site (37%), Skin reactions at application site (16.1%), Blisters under skin (12%)
1-10%
Erythema at application site (7%), Vesicles at application site (6%), Allergic contact dermatitis (4%), Burning at application site (3%), Induration at application site (3%)
Frequency Not Defined
Abnormal dreams, Acne, Anaphylaxis, Bladder irritability, Breast soreness, Cholestatic jaundice, Deep vein thrombosis,
Dry skin, Fatigue, Gynecomastia, Headache, Insomnia, Menstrual irregularities, Priapism, Suppression of factors II, V, VII, Virilization
Mechanism of Action
Testosterone is the principal endogenous androgen responsible for promoting the growth and development of male sexual organs and maintaining secondary sex characteristics in androgen-deficient males.
Note
Androgel 50mg Gel manufactured by SOLVAY PHARMACEUTICALS GmbH. Its generic name is Testosterone 1% Topical. Androgel is availble in United Arab Emirates.
Farmaco UAE drug index information on Androgel Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.