Apicarpin 2% Eye Drops (Solution)

Pilocarpine Hydrochloride 2 % Eye prep
20mg/ml
Amman Pharmaceutical Industries Co. Ltd.
Pack size 10ml Dropper Bottle
Dispensing mode POM
Source JORDAN
AgentARABIAN ETHICALS CO.
Retail Price 4.00 AED

Indications

Apicarpin 2% Eye Drops (Solution) is used for: Open-angle glaucoma

Adult Dose

Ophthalmic Open-angle glaucoma Adult: Apply 1-2 drops into the affected eye/s up to 4 times daily, adjusted according to response.

Child Dose

Safety and efficacy not established

Renal Dose

Administration

Contra Indications

Angle-closure glaucoma; acute iritis, anterior uveitis; hypersensitivity. Pregnancy.

Precautions

Retinal detachment; corneal or conjunctival damage. Prolonged use may lead to lens opacities. May impair ability to drive or operate machines. Lactation. Lactation: Excretion in breast milk unknown; use with caution

Pregnancy-Lactation

Pregnancy Category: C Lactation: Excretion in breast milk unknown; use with caution

Interactions

Concomitant admin of 2 miotics may increase risk of toxic reactions. Aminoglycosides, clindamycin, colistin, cyclopropane and halogenated inhalational anaesthetics, quinine, procainamide, lithium and beta-blockers may reduce the efficacy of pilacarpine. Concurrent use with beta-blockers may lead to bradycardia. May prolong the action of suxamethonium. Potentially Fatal: Miotic and ocular hypotensive effect antagonised by anticholinergics. Conduction disturbances with beta-blockers.

Adverse Effects

Side effects of Pilocarpine Hydrochloride 2 % Eye prep : Pain and irritation, blurred vision, lachrymation, browache, conjunctival vascular congestion, superficial keratitis, vitreous haemorrhage, increased pupillary block, Lacrimation, Salivation, Nausea, Vomiting, Headache, Bronchial spasm

Mechanism of Action

Pilocarpine is a tertiary parasympathomimetic that directly stimulates cholinergic receptors in the eyes causing pupillary constriction, spasm of accommodation and a transient rise in IOP followed by a fall.

Note

Apicarpin 2% 20mg/ml Eye Drops (Solution) manufactured by Amman Pharmaceutical Industries Co. Ltd.. Its generic name is Pilocarpine Hydrochloride 2 % Eye prep. Apicarpin 2% is availble in United Arab Emirates. Farmaco UAE drug index information on Apicarpin 2% Eye Drops (Solution) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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