Apicarpin 4% Eye Drops (Solution)
Pilocarpine Hydrochloride 4% Eye prep
40mg/ml
Amman Pharmaceutical Industries Co. Ltd.
| Pack size | 10ml Dropper Bottle |
|---|---|
| Dispensing mode | POM |
| Source | JORDAN |
| Agent | ARABIAN ETHICALS CO. |
| Retail Price | 4.00 AED |
Indications
Apicarpin 4% Eye Drops (Solution) is used for:
Open-angle glaucoma
Adult Dose
Ophthalmic
Open-angle glaucoma
Adult: Apply 1-2 drops into the affected eye/s up to 4 times daily, adjusted according to response.
Child Dose
Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Angle-closure glaucoma; acute iritis, anterior uveitis; hypersensitivity. Pregnancy.
Precautions
Retinal detachment; corneal or conjunctival damage. Prolonged use may lead to lens opacities. May impair ability to drive or operate machines. Lactation.
Lactation: Excretion in breast milk unknown; use with caution
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Excretion in breast milk unknown; use with caution
Interactions
Concomitant admin of 2 miotics may increase risk of toxic reactions. Aminoglycosides, clindamycin, colistin, cyclopropane and halogenated inhalational anaesthetics, quinine, procainamide, lithium and beta-blockers may reduce the efficacy of pilacarpine. Concurrent use with beta-blockers may lead to bradycardia. May prolong the action of suxamethonium.
Potentially Fatal: Miotic and ocular hypotensive effect antagonised by anticholinergics. Conduction disturbances with beta-blockers.
Adverse Effects
Side effects of Pilocarpine Hydrochloride 4% Eye prep :
Pain and irritation, blurred vision, lachrymation, browache, conjunctival vascular congestion, superficial keratitis, vitreous haemorrhage, increased pupillary block, Lacrimation, Salivation, Nausea, Vomiting, Headache, Bronchial spasm
Mechanism of Action
Pilocarpine is a tertiary parasympathomimetic that directly stimulates cholinergic receptors in the eyes causing pupillary constriction, spasm of accommodation and a transient rise in IOP followed by a fall.
Note
Apicarpin 4% 40mg/ml Eye Drops (Solution) manufactured by Amman Pharmaceutical Industries Co. Ltd.. Its generic name is Pilocarpine Hydrochloride 4% Eye prep. Apicarpin 4% is availble in United Arab Emirates.
Farmaco UAE drug index information on Apicarpin 4% Eye Drops (Solution) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.