Aprinox Tablets
Bendroflumethiazide (Bendrofluazide)
5mg
Boots Co PLC
| Pack size | 100's |
|---|---|
| Dispensing mode | POM |
| Source | UK |
| Agent | AL BAKER TRADING EST. |
| Retail Price | 9.50 AED |
Indications
Aprinox Tablets is used for:
Oedema, hypertension
Adult Dose
Oedema, initially 5–10 mg in the morning daily or on alternate days; maintenance, 2.5–10 mg 1–3 times weekly.
Hypertension, 2.5–5 mg in the morning
Nigerian Standard Treatment Guidelines 2016 recommendations:
Hypertension: 2.5 - 10 mg by mouth daily
Child Dose
Child (12 to 18 years):
Oedema, 5–10 mg daily or on alternate days
Hypertension, 2.5 mg daily
Renal Dose
Administration
For Oral use.
Administer in the morning to avoid interference with sleep or nocturia.
Advise patient to take drug with food to prevent nausea, and to eat food rich in potassium viz tomatoes, bananas, oranges
Contra Indications
Severe renal dysfunction, hypercalcaemia
Precautions
Potassium supplement may be required;
Diabetes;
Pregnancy, breastfeeding, elderly
Pregnancy-Lactation
Recommendations on the use of Bendroflumethiazide in Pregnancy & Lactation:
Available data do not suggest any teratogenic effects associated with the use of Bendroflumethiazide in the first trimester. However, it can cause maternal hypovolemia, and hypoglycaemia, thrombocytopaenia, hyponatraemia and hypokalaemia in the neonate. It is therefore better avoided in pregnancy (Briggs & Freeman, 2015).
Though, no adverse effects have been reported in the exposed breastfed infant, Bendroflumethiazide can cause suppression of lactation (Briggs & Freeman, 2015).
Reference:
1. Briggs, G. G., & Freeman, R. K. (2015). Drugs in pregnancy and lactation: A reference guide to fetal and neonatal risk (Tenth edition). Wolters Kluwer/Lippincott Williams & Wilkins Health
Interactions
Adverse Effects
Side effects of Bendroflumethiazide (Bendrofluazide) :
Hypokalaemia, gout, fatigue, blood dyscrasias, rash, hyperglycaemia
Mechanism of Action
Note
Aprinox 5mg Tablets manufactured by Boots Co PLC. Its generic name is Bendroflumethiazide (Bendrofluazide). Aprinox is availble in United Arab Emirates.
Farmaco UAE drug index information on Aprinox Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.