Argiderm P Cream
Silver sulphadiazine, Panthenol
"10mg, 50mg/g"
AMOUN PHARMACEUTICAL CO.S.A.E.
| Pack size | 15g Collapsible Tube |
|---|---|
| Dispensing mode | POM |
| Source | EGYPT |
| Agent | Modern Pharmaceutical Co. |
| Retail Price | 3.00 AED |
Available as:
Indications
Argiderm P Cream is used for:
SILVER SULFADIAZINE
Indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns
DEXPANTHENOL
Panthenol is used as a moisturizer and to improve wound healing in pharmaceutical and cosmetic products
Indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns
DEXPANTHENOL
Panthenol is used as a moisturizer and to improve wound healing in pharmaceutical and cosmetic products
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Silver sulphadiazine, Panthenol :
Mechanism of Action
SILVER SULFADIAZINE
Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemical techniques have revealed that the mechanism of action of silver sulfadiazine on bacteria differs from silver nitrate and sodium sulfadiazine. Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect. A specific mechanism of action has not been determined, but silver sulfadiazine's effectiveness may possibly be from a synergistic interaction, or the action of each component. Silver is a biocide, which binds to a broad range of targets. Silver ions bind to nucleophilic amino acids, as well as sulfhydryl, amino, imidazole, phosphate, and carboxyl groups in proteins, causing protein denaturation and enzyme inhibition. Silver binds to surface membranes and proteins, causing proton leaks in the membrane, leading to cell death. Sulfadiazine is a competitive inhibitor of bacterial para-aminobenzoic acid (paba), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid
DEXPANTHENOL
Panthenol readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid. Pantothenic acid is extremely hygroscopic, that is, it binds water effectively. It is also used in the biosynthesis of coenzyme a, which plays a role in a wide range of enzymatic reactions and thus in cell growth
Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemical techniques have revealed that the mechanism of action of silver sulfadiazine on bacteria differs from silver nitrate and sodium sulfadiazine. Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect. A specific mechanism of action has not been determined, but silver sulfadiazine's effectiveness may possibly be from a synergistic interaction, or the action of each component. Silver is a biocide, which binds to a broad range of targets. Silver ions bind to nucleophilic amino acids, as well as sulfhydryl, amino, imidazole, phosphate, and carboxyl groups in proteins, causing protein denaturation and enzyme inhibition. Silver binds to surface membranes and proteins, causing proton leaks in the membrane, leading to cell death. Sulfadiazine is a competitive inhibitor of bacterial para-aminobenzoic acid (paba), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid
DEXPANTHENOL
Panthenol readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid. Pantothenic acid is extremely hygroscopic, that is, it binds water effectively. It is also used in the biosynthesis of coenzyme a, which plays a role in a wide range of enzymatic reactions and thus in cell growth
Note
Argiderm P "10mg, 50mg/g" Cream manufactured by AMOUN PHARMACEUTICAL CO.S.A.E.. Its generic name is Silver sulphadiazine, Panthenol. Argiderm P is availble in United Arab Emirates.
Farmaco UAE drug index information on Argiderm P Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.