Aten Tablets (Caplets)

Atenolol
50mg
CADILA HEALTH CARE LIMITED
Pack size 30's Plastic Bottle
Dispensing mode POM
Source INDIA
AgentDUPHARM
Retail Price 14.00 AED

Available as:

25mg - Tablets (Caplets) 100mg - Tablets (Caplets)

Indications

Aten Tablets (Caplets) is used for: Hypertension, Migraine, Arrhythmias, MI, Angina pectoris

Adult Dose

Adult Hypertension 25-50 mg/day PO initially; may be increased to 100 mg/day PO Angina Pectoris 50 mg/day PO; after 1 week, may be increased to 100 mg/day PO; some patients may require 200 mg/day Post Myocardial Infarction Secondary prevention 100 mg PO once daily or divided q12hr for 6-9 days after myocardial infarction (MI) Elderly May be necessary to initiate dosing at 25 mg/day PO Hypertension 25 mg/day PO initially; may be increased to 100 mg/day PO Angina Pectoris 25 mg/day PO; after 1 week, may be increased to 100 mg/day; some patients may require 200 mg/day Post Myocardial Infarction Secondary prevention 100 mg PO once daily or divided q12hr for 6-9 days after MI

Child Dose

Renal Dose

Renal impairment: CrCl (ml/min) <15 25 mg or 50 mg on alternate days. 15-35 50 mg/day. Dialysis patients 25-50 mg after each dialysis.

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity. Sinus bradycardia, sinus node dysfunction, heart block >1st degree, compensated cardiac failure, cardiogenic shock, bronchospastic diseases, peripheral vascular diseases. Pregnancy.

Precautions

Compensated heart failure. Variant angina, acute MI, DM; peripheral vascular disorders; hepatic and renal dysfunction; elderly patients, children. Lactation. If atenolol and clonidine are co-admin, then gradual withdrawal of clonidine should take place a few days after withdrawal of atenolol. Lactation: Drug enters breast milk; neonates born to mothers who are receiving atenolol at parturition or breastfeeding may be at risk for hypoglycemia and bradycardia; use with caution

Pregnancy-Lactation

Pregnancy category: D Lactation: Drug enters breast milk; neonates born to mothers who are receiving atenolol at parturition or breastfeeding may be at risk for hypoglycemia and bradycardia; use with caution

Interactions

Concomitant admin w/ reserpine may increase hypotension and bradycardia. Additive w/ Ca channel blockers, hydralazine, methyldopa. Increased risk of bradycardia and heart block w/ verapamil and diltiazem. May decrease hypotensive effects w/ NSAIDs (e.g. indometacin). Enhanced bradycardic effect w/ disopyramide, amiodarone or digitalis glycosides. May exacerbate rebound HTN upon discontinuance of clonidine treatment.

Adverse Effects

Side effects of Atenolol : >10% Tiredness (13%) 1-10% Hypotension (10%), Bradycardia (8%), Cold extremities (0.5- 7%), Postural hypotension (2-4%), Depression (3%), Nausea (2-3%), Dreaming (2%), Drowsiness (2%), Diarrhea (1-2%), Fatigue (1-2%), Leg pain (1-2%), Lethargy (1-2%), Lightheadedness (1-2%), Vertigo (1-2%), Dyspnea (0.4-2%), 2°/3° atrioventricular (AV) block (1%) Frequency Not Defined Hypotension, severe congestive heart failure (CHF), sick sinus syndrome, Catatonia, disorientation, emotional lability, hallucinations, headache, impaired performance on neuropsychometric tests, psychoses, short-term memory impairment, Purpura, rashes, Nausea, Thrombocytopenia, Elevated serum hepatic enzymes and bilirubin, Impotence, Peyronie disease, Antinuclear antibodies (ANA), lupus syndrome, Visual disturbances, xerophthalmia, Raynaud phenomenon Potentially Fatal: Heart failure, 2nd or 3rd degree AV block.

Mechanism of Action

Atenolol is a competitive cardioselective beta1-blocker and does not have effect on ?beta2-receptors except in high doses. It reduces resting and exercise-induced heart rate as well as myocardial contractility.

Note

Aten 50mg Tablets (Caplets) manufactured by CADILA HEALTH CARE LIMITED. Its generic name is Atenolol. Aten is availble in United Arab Emirates. Farmaco UAE drug index information on Aten Tablets (Caplets) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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