Axid Capsules (Hard Gelatin)

Nizatidine

300mg

LILLY SA

Pack size	14's Blister
Dispensing mode	POM
Source	SPAIN
Agent	PHARMATRADE
Retail Price	73.50 AED

Available as:

150mg - Capsules (Hard Gelatin)

Indications

Axid Capsules (Hard Gelatin) is used for: Benign gastric and duodenal ulceration, Gastro-oesophageal reflux disease

Adult Dose

Oral Benign gastric and duodenal ulceration; NSAID-associated ulceration Adult: 300 mg at bedtime or in 2 divided doses for 4-8 wk. Maintenance: 150 mg at bedtime. Gastro-oesophageal reflux disease Adult: 150-300 mg bid for up to 12 wk.

Child Dose

GERD <12 years: 5-10 mg/kg/day PO divided q12h

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <20 150 mg every other day. Maintenance: 150 mg every 3 days. 20-50 150 mg/day. Maintenance: 150 mg every other day.

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity.

Precautions

Possibility of malignancy should be excluded prior to therapy as the drug may mask symptoms and delay diagnosis of gastric malignancy. Increased risk of community-acquired pneumonia. Renal impairment. Pregnancy and lactation. Patient Counselling May impair ability to drive, operate machinery and perform hazardous tasks. Lactation: crosses into breast milk, either discontinue nursing or the drug

Pregnancy-Lactation

Interactions

May increase absorption of aspirin when used in high-doses. May decrease bioavailability w/ antacids.

Adverse Effects

Side effects of Nizatidine : >10% Headache (17%) 1-10% Abdominal pain, Anxiety, Constipation, Diarrhea, Dizziness, Insomnia, Nausea/vomiting, Pruritus <1% Anemia, Increased LFT's Potentially Fatal: Anaphylaxis.

Mechanism of Action

Nizatidine is a histamine H2-receptor antagonist. It blocks histamine H2-receptors on gastric parietal cells resulting in decreased gastric acid secretion, gastric volume and hydrogen ion concentration.

Note

Axid 300mg Capsules (Hard Gelatin) manufactured by LILLY SA. Its generic name is Nizatidine. Axid is availble in United Arab Emirates. Farmaco UAE drug index information on Axid Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Nizatidine :

Capsules (Hard Gelatin)

Fixit ^75mg

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Capsules (Hard Gelatin)

Fixit ^300mg

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Fixit ^150mg

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Capsules (Hard Gelatin)

ELI LILLY ITALIA S.p.A.