Bactroban 2% Cream

Mupirocin 2% Topical

20mg/g

SMITHKLINE BEECHAM PHARMACEUTICALS

Pack size	15g Tube
Dispensing mode	POM
Source	UK
Agent	AL ITTIHAD DRUG STORE
Retail Price	28.00 AED

Indications

Bactroban 2% Cream is used for: Impetigo, Folliculitis, Secondary skin infections

Adult Dose

Topical/Cutaneous Impetigo Adult: As 2% oint: Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response. Secondary skin infections Adult: As 2% cream: Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.

Child Dose

Topical/Cutaneous Impetigo Child: >2 mth Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response. Secondary skin infections Child: >3 mth Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.

Renal Dose

Administration

Contra Indications

This drug is contraindicated in individuals with a history of sensitivity reactions to Mupirocin or any of the components of the preparation.

Precautions

Patient w/ extensive burns and wounds. Renal impairment. Childn. Pregnancy and lactation. Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi Lactation: Not known if distributed into milk; recommended that nursing be temporarily discontinued during therapy

Pregnancy-Lactation

Pregnancy There are insufficient human data to establish whether there is drug-associated risk with therapy in pregnant women; systemic absorption of mupirocin through intact human skin is minimal following topical administration of mupirocin ointment; no developmental toxicity was observed in rats or rabbits treated with mupirocin subcutaneously during organogenesis at doses of 160 or 40 mg per kg per day, respectively (22 and 11 times the human topical dose based on calculations of dose divided by the entire body surface area) Lactation Not known whether mupirocin is present in human milk, has effects on breastfed child, or has effects on milk production; however, breastfeeding is not expected to result in exposure of child to drug due to minimal systemic absorption following topical administration; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on breastfed child from therapy or from underlying maternal condition To minimize oral exposure of drug to children, a breast and/or nipple being treated with mupirocin ointment should be thoroughly washed prior to breastfeeding

Interactions

Adverse Effects

Side effects of Mupirocin 2% Topical : Burning, stinging, pruritus, pain, rash, erythema, dry skin, tenderness, cellulitis, pain or bleeding secondary to eczema, secondary wound infection, urticaria, swelling, increased exudates, contact dermatitis, furunculosis, exfoliative dermatitis. Rarely, systemic reactions (e.g. nausea, headache, dizziness, abdominal pain, ulcerative stomatitis, systemic allergic reactions).

Mechanism of Action

Mupirocin inhibits protein synthesis of the bacteria by binding to isoleucyl transfer RNA-synthetase. It is active against gram-positive and some gram-negative bacteria.

Note

Bactroban 2% 20mg/g Cream manufactured by SMITHKLINE BEECHAM PHARMACEUTICALS. Its generic name is Mupirocin 2% Topical. Bactroban 2% is availble in United Arab Emirates. Farmaco UAE drug index information on Bactroban 2% Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Mupirocin 2% Topical :

Ointment

Supirocin 2% ^20mg/g

GLENMARK PHARMACEUTICALS LIMITED

Ointment

Supirocin 2% ^20mg/g

GLENMARK PHARMACEUTICALS LIMITED

Avoban 2% Ointment ^{20 mg/g}

MIDDLE EAST PHARM. INDUSTRIES CO.LIMITED (AVALON PHARMA)