Carbaglu Tablets / Dispersible
Carglumic acid200 mg/Tablet
200mg
Orphan Europe
| Pack size | 5's HDPE Bottles |
|---|---|
| Dispensing mode | POM |
| Source | FRANCE |
| Agent | PHARMALINK |
| Retail Price | 2402.50 AED |
Available as:
Indications
Carbaglu Tablets / Dispersible is used for:
For the treatment of acute and chronic hyperammonaemia in patients with N-acetylglutamate synthase (NAGS) deficiency. This enzyme is an important component of the urea cycle to prevent build up of neurotoxic ammonium in the blood.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Carglumic acid200 mg/Tablet :
Mechanism of Action
Carglumic acid is a synthetic structural analogue of N-acetylglutamate (NAG), which is an essential allosteric activator of the liver enzyme carbamoyl phosphate synthetase 1 (CPS1). CPS1 is found in the mitochondria and is the first enzyme of the urea cycle, which converts ammonia into urea. Carglumic acid acts as a replacement for NAG in NAGS deficiency patients by activating CPS1 but it does not help to regulate the urea cycle.
Note
Carbaglu 200mg Tablets / Dispersible manufactured by Orphan Europe . Its generic name is Carglumic acid200 mg/Tablet. Carbaglu is availble in United Arab Emirates.
Farmaco UAE drug index information on Carbaglu Tablets / Dispersible is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.