Cetrotide Infusion
Cetrorelix
0.25mg
BAXTER ONCOLOGY GmbH
| Pack size | 1 Vial (Dry) + 1 Solvent Syringe (1ml) + 2 Needles |
|---|---|
| Dispensing mode | POM |
| Source | GERMANY |
| Agent | ARABIAN ETHICALS CO. |
| Retail Price | 194.00 AED |
Indications
Cetrotide Infusion is used for:
Assisted reproductive technologies, In-vitro fertilization
Adult Dose
Subcutaneous
Assisted reproductive technologies
Adult: As acetate: equiv to 0.25 mg cetrorelix either in the morning beginning on the day 5 or 6 of ovarian stimulation or in the evening beginning on day 5, and continued until ovulation induction.
Child Dose
Renal Dose
Severe renal impairment: Contraindicated
Administration
Contra Indications
Hypersensitivity. Moderate to severe renal or hepatic impairment. Women with severe allergic conditions. Pregnancy and lactation;
Precautions
Women with active allergic conditions or a history of allergies; childn; elderly >65 yrs
Lactation: Excretion in milk unknown/contraindicated
Pregnancy-Lactation
Pregnancy Category: X
Lactation: Excretion in milk unknown/contraindicated
Interactions
In vitro investigations have shown that interactions are unlikely with medications that are metabolised by cytochrome P-450 or glucuronised or conjugated in some other way. However, the possibility of interactions with commonly used medicinal products can not entirely be excluded.
Adverse Effects
Side effects of Cetrorelix :
1-10%
Ovarian hyperstimulation syndrome (4%), Nausea (1%), Hepatic enzyme elevation (1-2%), Headache (1%)
<1%
Erythema at injection site, Itching, Pruritus, Swelling, Redness, Hypotension, Rash, Cough
Mechanism of Action
Cetrorelix, a synthetic decapeptide analog of naturally occurring gonadorelin, is a gonadorelin antagonist. It competitively blocks gonadorelin receptors on the anterior piyuitary gonadotroph and the subsequent transduction pathway, inducing a rapid, reversible suppression of gonadotrophin secretion.
Note
Cetrotide 0.25mg Infusion manufactured by BAXTER ONCOLOGY GmbH. Its generic name is Cetrorelix. Cetrotide is availble in United Arab Emirates.
Farmaco UAE drug index information on Cetrotide Infusion is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.