Colfed Syrup

Cold - Pseudoephedrine HCl, Triprolidine HCl
"30mg, 1.25mg/5ml"
The Arab Parm. Mfg. Co (APM)
Pack size 120ml Glass Bottle
Dispensing mode POM
Source JORDAN
AgentModern Pharmaceutical Co.
Retail Price 5.50 AED

Indications

Colfed Syrup is used for: PSEUDOEPHEDRINE
For the treatment of nasal congestion, sinus congestion, eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism
TRIPROLIDINE
For the symptomatic relief of seasonal or perennial allergic rhinitis or nonallergic rhinitis; allergic conjunctivitis; and mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Also used in combination with other agents for the symptomatic relief of symptoms associated with the common cold

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Cold - Pseudoephedrine HCl, Triprolidine HCl :

Mechanism of Action

PSEUDOEPHEDRINE
Pseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. Through direct action on alpha-adrenergic receptors in the mucosa of the respiratory tract, pseudoephedrine produces vasoconstriction. Pseudoephedrine relaxes bronchial smooth muscle by stimulating beta2-adrenergic receptors. Like ephedrine, pseudoephedrine releasing norepinephrine from its storage sites, an indirect effect. This is its main and direct mechanism of action. The displaced noradrenaline is released into the neuronal synapse where it is free to activate the postsynaptic adrenergic receptors
TRIPROLIDINE
Triprolidine binds to the histamine h1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine

Note

Colfed "30mg, 1.25mg/5ml" Syrup manufactured by The Arab Parm. Mfg. Co (APM). Its generic name is Cold - Pseudoephedrine HCl, Triprolidine HCl. Colfed is availble in United Arab Emirates. Farmaco UAE drug index information on Colfed Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Cold - Pseudoephedrine HCl, Triprolidine HCl :