Concor Am 5/5 Tablets

Bisoprolol + Amlodipine
"5mg, 5mg"
MERCK KgaA
Pack size 30's(10's Blister x 3)
Dispensing mode POM
Source HUNGARY
AgentModern Pharmaceutical Co.
Retail Price 41.50 AED

Indications

Concor Am 5/5 Tablets is used for: Treatment of mild to moderate hypertension

Adult Dose

Oral Adult 1 tablet once daily

Child Dose

Renal Dose

Administration

Contra Indications

Cardiogenic shock, overt cardiac failure, second or third degree AV block, and marked sinus bradycardia and known sensitivity to amlodipine/bisoprolol.

Precautions

Bisoprolol: Overt congestive cardiac failure, abrupt cessation of therapy, peripheral vascular disease, bronchospastic disease, anesthesia and major surgery, diabetes and hypoglycaemia and thyrotoxicosis. Amlodipine: Severe aortic stenosis, congestive heart failure and hepatic failure This medicine is not recommended for use in breastfeeding women unless absolutely necessary.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Bisoprolol + Amlodipine : Edema, headache, increase heart rate, sneezing, fatigue, leg cramps, dry mouth. Other adverse events reported were gastric irritation, angina, asthma, cold extremities, cough, decrease in libido, dizziness, facial flushing, postural hypotension, skin rash, sleep disturbance and vertigo.

Mechanism of Action

Bisoprolol selectively and competitively blocks β1-receptors but has little or no effect on β2-receptors except at high doses. Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.

Note

Concor Am 5/5 "5mg, 5mg" Tablets manufactured by MERCK KgaA. Its generic name is Bisoprolol + Amlodipine. Concor Am 5/5 is availble in United Arab Emirates. Farmaco UAE drug index information on Concor Am 5/5 Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Bisoprolol + Amlodipine :