Concor Am 5/5 Tablets
Bisoprolol + Amlodipine
"5mg, 5mg"
MERCK KgaA
| Pack size | 30's(10's Blister x 3) |
|---|---|
| Dispensing mode | POM |
| Source | HUNGARY |
| Agent | Modern Pharmaceutical Co. |
| Retail Price | 41.50 AED |
Available as:
Indications
Concor Am 5/5 Tablets is used for:
Treatment of mild to moderate hypertension
Adult Dose
Oral
Adult
1 tablet once daily
Child Dose
Renal Dose
Administration
Contra Indications
Cardiogenic shock, overt cardiac failure, second or third degree AV block, and marked sinus bradycardia and known sensitivity to amlodipine/bisoprolol.
Precautions
Bisoprolol: Overt congestive cardiac failure, abrupt cessation of therapy, peripheral vascular disease, bronchospastic disease, anesthesia and major surgery, diabetes and hypoglycaemia and thyrotoxicosis.
Amlodipine: Severe aortic stenosis, congestive heart failure and hepatic failure
This medicine is not recommended for use in breastfeeding women unless absolutely necessary.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Bisoprolol + Amlodipine :
Edema, headache, increase heart rate, sneezing, fatigue, leg cramps, dry mouth. Other adverse events reported were gastric irritation, angina, asthma, cold extremities, cough, decrease in libido, dizziness, facial flushing, postural hypotension, skin rash, sleep disturbance and vertigo.
Mechanism of Action
Bisoprolol selectively and competitively blocks β1-receptors but has little or no effect on β2-receptors except at high doses.
Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.
Note
Concor Am 5/5 "5mg, 5mg" Tablets manufactured by MERCK KgaA. Its generic name is Bisoprolol + Amlodipine. Concor Am 5/5 is availble in United Arab Emirates.
Farmaco UAE drug index information on Concor Am 5/5 Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.