CONVERIUM Tablets

Irbesartan
150mg
MEDOCHEMIE LTD.
Pack size 30's (10's Blister x 3)
Dispensing mode POM
Source CYPRUS
AgentARABIAN ETHICALS CO.
Retail Price 64.00 AED

Available as:

Indications

CONVERIUM Tablets is used for: Diabetic nephropathy, Hypertension

Adult Dose

Oral Hypertension Adult: 150 mg once daily, may increase to 300 mg once daily if needed. Patient w/ intravascular volume depletion: Initially, 75 mg once daily. Elderly: >75 yr Initially, 75 mg once daily. Diabetic nephropathy in Type 2 diabetes mellitus Adult: Initially, 75-150 mg once daily, may increase to 300 mg once daily if needed.

Child Dose

Hypertension <6 years: Safety and efficacy not established 6-12 years: 75 mg/day PO initially; not to exceed 150 mg/day >12 years: 150 mg/day PO initially; may be increased to 300 mg/day PO

Renal Dose

Renal impairment: Haemodialysis: Initially, 75 mg once daily. Mild-to-severe renal impairment: Dosage adjustment not necessary unless patient is hypovolemic

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity; pregnancy and lactation.

Precautions

Child <6 yr. Unilateral or bilateral renal artery stenosis; vol or Na depletion; aortic or mitral valve stenosis, hypertrophic cardiomyopathy. Lactation: Potential harm to nursing infant; discontinue drug, or do not nurse

Pregnancy-Lactation

Pregnancy category: 1st trimester, C; 2nd and 3rd trimesters, D

Interactions

May antagonise hypotensive effect and increase risk of nephrotoxicity w/ NSAIDs. May increase serum lithium levels and toxicity. Increased risk of hyperkalaemia w/ K-sparing diuretics (e.g. amiloride, triamterene, spironolactone), K supplements or K-containing salt substitutes. Potentially Fatal: May increase nephrotoxic, hyperkalaemic and hypotensive effect w/ aliskiren in patients w/ diabetes and renal impairment (GFR <60 mL/min).

Adverse Effects

Side effects of Irbesartan : >10% Hyperkalemia (19%) 1-10% Dizziness (10%), Upper respiratory tract infection (URTI) (9%), Orthostatic hypotension (5%), Fatigue (4%), Diarrhea (3%), Dyspepsia (2%)

Mechanism of Action

Irbesartan is an angiotensin II receptor antagonist. It blocks the vasoconstricting and aldosterone-secreting effects of angiotensin II by binding to AT1 receptors.

Note

CONVERIUM 150mg Tablets manufactured by MEDOCHEMIE LTD.. Its generic name is Irbesartan. CONVERIUM is availble in United Arab Emirates. Farmaco UAE drug index information on CONVERIUM Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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