CUTIVATE 0.005% Ointment

Fluticasone Propionate 0.005% Topical
0.05mg/g
GLAXO OPERATIONS UK LTD.
Pack size 15g Tube
Dispensing mode POM
Source UK
AgentAL BAKER TRADING EST.
Retail Price 6.00 AED

Available as:

Indications

CUTIVATE 0.005% Ointment is used for: Psoriasis, Eczema, Corticosteroid-responsive dermatoses

Adult Dose

Topical ointment Atopic Dermatitis, Corticosteroid-responsive Dermatoses Apply a thin film to the affected skin areas once or twice daily. Rub in gently. Reassess diagnosis if no improvements within 2 weeks

Child Dose

Topical ointment Atopic Dermatitis, Corticosteroid-responsive Dermatoses Child > 1 year: Apply a thin film to the affected skin areas once or twice daily.

Renal Dose

Administration

Contra Indications

Fluticasone Propionate ointment is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.

Precautions

Fluticasone Propionate ointment may cause local cutaneous adverse reactions. If irritation develops, Fluticasone Propionate ointment should be discontinued. Fluticasone Propionate ointment should not be used in the presence of preexisting skin atrophy and should not be used where infection is present at the treatment site. This should not be used in the treatment of rosacea and perioral dermatitis. Lactation: Excretion in milk unknown; use with caution

Pregnancy-Lactation

Pregnancy Category: C Lactation: Excretion in milk unknown; use with caution

Interactions

May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.

Adverse Effects

Side effects of Fluticasone Propionate 0.005% Topical : 1-10% Pruritus (2.9%), Dryness (1.2%), Skin irritation: (3%), Eczema (1%), Telangiectasia (2-5%), Numbness of fingers (1%) <1% Burning, Folliculitis, Acneiform lesions, Urticaria, Hypertrichosis, Lightheadedness, Viral, Warts, Impetigo, Skin infection Frequency Not Defined Striae, Pigmentation changes, HPA suppression (with higher potency used >2 wk), Erythema, Cushing syndrome, Sepsis, Hemorrhage reported, Edema/swelling

Mechanism of Action

Fluticasone Propionate is a synthetic, trifluorinated corticosteroid that provides anti-inflammatory activity. It binds to glucocorticoid receptor and inhibits the migration of inflammatory mediator & cells (histamine, leukotrienes, mast cells, eosinophils etc).

Note

CUTIVATE 0.005% 0.05mg/g Ointment manufactured by GLAXO OPERATIONS UK LTD.. Its generic name is Fluticasone Propionate 0.005% Topical. CUTIVATE 0.005% is availble in United Arab Emirates. Farmaco UAE drug index information on CUTIVATE 0.005% Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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