Dalacin 2% Vaginal Cream
Clindamycin 2% Vaginal prep
20mg/g
PHARMACIA & UPJOHN COMPANY
| Pack size | 40g Tube + 7 Applicators |
|---|---|
| Dispensing mode | POM |
| Source | USA |
| Agent | Modern Pharmaceutical Co. |
| Retail Price | 58.50 AED |
Available as:
Indications
Dalacin 2% Vaginal Cream is used for:
Bacterial vaginosis
Adult Dose
Bacterial Vaginosis
Vaginal cream: 1 full applicator inserted (approximately 5 gram) intravaginally at bedtime for 3 days in nonpregnant patients and for 7 days in pregnant patients
Child Dose
<12 years old
Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity.Clindamycin cream is also contraindicated in individuals with a history of regional enteritis, ulcerative colitis, or a history of \"antibiotic-associated\" colitis.
Precautions
The patient should be instructed not to engage in vaginal intercourse, or use other vaginal products during treatment with this product. This cream contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms. Therefore, use of such products within 72 hours following treatment with Clindacin cream is not recommended.
Lactation: Excretion in milk unknown; use with caution
Pregnancy-Lactation
Interactions
May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione).
Adverse Effects
Side effects of Clindamycin 2% Vaginal prep :
Genital tract: vaginitis, vulvo-vaginal irritation
Central nervous system: dizziness, headache, vertigo.
Gastro-intestinal: heartburn, nausea, vomiting, diarrhea, constipation, abdominal pain.
Dermatological: rash, exanthema.
Hypersensitivity: urticaria.
Mechanism of Action
Clindamycin inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosomal thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting to stunted cell growth.
Note
Dalacin 2% 20mg/g Vaginal Cream manufactured by PHARMACIA & UPJOHN COMPANY. Its generic name is Clindamycin 2% Vaginal prep. Dalacin 2% is availble in United Arab Emirates.
Farmaco UAE drug index information on Dalacin 2% Vaginal Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.