De-Nol Tablets

Bismuth Subcitrate
120mg
YAMANOUCHI EUROPE B.V.
Pack size 120's (8's Blister x 15)
Dispensing mode POM
Source NETHERLANDS
AgentCITY MEDICAL STORE
Retail Price 191.50 AED

Available as:

Indications

De-Nol Tablets is used for: Gastric and duodenal ulceration, H.pylori infection, Peptic ulcers

Adult Dose

Adult: PO Benign gastric and duodenal ulceration 240 mg twice daily for 4-8 wk. H.pylori infection W/ other drugs: 120 mg 4 times/day for 2 wk.

Child Dose

Renal Dose

Renal impairment: Moderate-severe impairment: Avoid use.

Administration

Contra Indications

Moderate-severe renal insufficiency. Pregnancy, child <14 yr.

Precautions

Lactation. Monitor renal function regularly. Lactation: Poorly absorbed in to system circulation

Pregnancy-Lactation

Interactions

Food, milk, antacids, tetracyclines and H2-receptor antagonists reduce activity of drug.

Adverse Effects

Side effects of Bismuth Subcitrate : Darkening of tongue or stools. Nausea, vomiting, bone and joint toxicity. Potentially Fatal: Possibility of bismuth poisoning and fatal encephalopathy in patients with renal impairment or if given over prolonged periods. Renal failure and liver damage.

Mechanism of Action

Bismuth subcitrate is used in the management of gastric and duodenal ulcers and specifically against H.pylori as part of a triple drug regimen. It exerts bactericidal action against H.pylori which is accepted to be the causative factor in chronic gastritis and duodenal ulcer..

Note

De-Nol 120mg Tablets manufactured by YAMANOUCHI EUROPE B.V.. Its generic name is Bismuth Subcitrate. De-Nol is availble in United Arab Emirates. Farmaco UAE drug index information on De-Nol Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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