Decoderm Tri Cream
Fluprednidene (as acetate), Miconazole nitrate
"1mg, 20mg/g"
ALMIRALL HERMAL GmbH
| Pack size | 25g Aluminium Tube |
|---|---|
| Dispensing mode | POM |
| Source | GERMANY |
| Agent | NEW MEDICAL CENTRE |
| Retail Price | 31.00 AED |
Indications
Decoderm Tri Cream is used for:
Miconazole
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Fluprednidene (as acetate), Miconazole nitrate :
Mechanism of Action
Miconazole
Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.
Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.
Note
Decoderm Tri "1mg, 20mg/g" Cream manufactured by ALMIRALL HERMAL GmbH. Its generic name is Fluprednidene (as acetate), Miconazole nitrate. Decoderm Tri is availble in United Arab Emirates.
Farmaco UAE drug index information on Decoderm Tri Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.