Dettol Cream
Chloroxylenol, Edetic acid, Triclosan
Combination
Reckitt Benckiser Healthcare (UK) Limited
| Pack size | 30g Tube |
|---|---|
| Dispensing mode | P |
| Source | UK |
| Agent | CITY MEDICAL STORE |
| Retail Price | AED |
Indications
Dettol Cream is used for:
CHLOROXYLENOL
Used to control bacteria, algae, fungi and virus. It is used in hospitals and households for disinfection and sanitation. It is also commonly used in antibacterial soaps, wound-cleansing applications and household antiseptics
TRICLOSAN
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes
Used to control bacteria, algae, fungi and virus. It is used in hospitals and households for disinfection and sanitation. It is also commonly used in antibacterial soaps, wound-cleansing applications and household antiseptics
TRICLOSAN
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Chloroxylenol, Edetic acid, Triclosan :
Mechanism of Action
CHLOROXYLENOL
Its antibacterial action is due to disruption of cell membrane potentials
TRICLOSAN
At in-use concentrations, triclosan acts as a biocide, with multiple cytoplasmic and membrane targets. At lower concentrations, however, triclosan appears bacteriostatic and is seen to target bacteria mainly by inhibiting fatty acid synthesis. Triclosan binds to bacterial enoyl-acyl carrier protein reductase enzyme (enr), which is encoded by the gene fabi. This binding increases the enzyme's affinity for nicotinamide adenine dinucleotide (nad+). This results in the formation of a stable ternary complex of enr-nad+-triclosan, which is unable to participate in fatty acid synthesis. Fatty acids are necessary for reproducing and building cell membranes. Humans do not have an enr enzyme, and thus are not affected
Its antibacterial action is due to disruption of cell membrane potentials
TRICLOSAN
At in-use concentrations, triclosan acts as a biocide, with multiple cytoplasmic and membrane targets. At lower concentrations, however, triclosan appears bacteriostatic and is seen to target bacteria mainly by inhibiting fatty acid synthesis. Triclosan binds to bacterial enoyl-acyl carrier protein reductase enzyme (enr), which is encoded by the gene fabi. This binding increases the enzyme's affinity for nicotinamide adenine dinucleotide (nad+). This results in the formation of a stable ternary complex of enr-nad+-triclosan, which is unable to participate in fatty acid synthesis. Fatty acids are necessary for reproducing and building cell membranes. Humans do not have an enr enzyme, and thus are not affected
Note
Dettol Combination Cream manufactured by Reckitt Benckiser Healthcare (UK) Limited. Its generic name is Chloroxylenol, Edetic acid, Triclosan. Dettol is availble in United Arab Emirates.
Farmaco UAE drug index information on Dettol Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.