DIMELOR Tablets
Acetohexamide
500mg
ELI LILLY & CO LTD.
Pack size | 20's |
---|---|
Dispensing mode | POM |
Source | UK |
Agent | PHARMATRADE |
Retail Price | 12.00 AED |
Indications
DIMELOR Tablets is used for:
Used in the management of diabetes mellitus type 2 (adult-onset).
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Acetohexamide :
Mechanism of Action
Sulfonylureas such as acetohexamide bind to an ATP-dependent K+ channel on the cell membrane of pancreatic beta cells. This inhibits a tonic, hyperpolarizing outflux of potassium, which causes the electric potential over the membrane to become more positive. This depolarization opens voltage-gated Ca2+ channels. The rise in intracellular calcium leads to increased fusion of insulin granulae with the cell membrane, and therefore increased secretion of (pro)insulin.
Note
DIMELOR 500mg Tablets manufactured by ELI LILLY & CO LTD.. Its generic name is Acetohexamide. DIMELOR is availble in United Arab Emirates.
Farmaco UAE drug index information on DIMELOR Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.