Dipentum Capsules (Hard Gelatin)
Olsalazine Sodium
250mg
PHARMACIA & UPJOHN AB.
| Pack size | 100's Bottle |
|---|---|
| Dispensing mode | POM |
| Source | SWEDEN |
| Agent | AL RAZI PHARMACY |
| Retail Price | 149.00 AED |
Indications
Dipentum Capsules (Hard Gelatin) is used for:
For the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Olsalazine Sodium :
Mechanism of Action
Orally administered olsalazine is converted to mesalamine which is thought to be the therapeutically active agent in the treatment of ulcerative colitis. The mechanism of action of mesalamine (and sulfasalazine) is unknown, but appears to be topical rather than systemic. Mucosal production of arachidonic acid (AA) metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes (LTs) and hydroxyelcosatetraenoic acids (HETEs) is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalamine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin (PG) production in the colon.
Note
Dipentum 250mg Capsules (Hard Gelatin) manufactured by PHARMACIA & UPJOHN AB.. Its generic name is Olsalazine Sodium. Dipentum is availble in United Arab Emirates.
Farmaco UAE drug index information on Dipentum Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.