DOLCIVIT 1000 Capsules (Soft Gelatin)

Cholecalciferol (Vit. D3)
1000 IU
GELTEC HEALTHCARE FZE
Pack size 60’s HDPE Bottle
Dispensing mode POM
Source UAE
AgentAL MUFID PHARMACEUTICALS
Retail Price AED

Available as:

1000 IU - Capsules (Soft Gelatin) 50000 IU - Capsules (Soft Gelatin)

Indications

DOLCIVIT 1000 Capsules (Soft Gelatin) is used for: Osteoporosis, Hypoparathyroidism, Rickets, Osteomalacia,Vitamin D Deficiency, Pseudohypoparathyroidism, Familial hypophosphatemia

Adult Dose

Oral /IM: Nutritional deficiency Colecalciferol (Vitamin D3) is recommended 5-10 mcg or 1-2ml (200-400 IU)/day Osteoporosis Prophylaxis and treatment >50 years: 800-1000 IU (20-25 mcg) PO once daily with calcium supplements. May also be given via IM inj. Hypoparathyroidism 50,000-200,000 IU (0.625-5 mg) PO once daily with calcium supplements. May also be given via IM inj.

Child Dose

Nutritional Supplementation RDA 0-12 months: 400 IU (10 mcg) PO once daily 1-18 years: 600 IU (15 mcg) PO once daily Vitamin D-Resistant Rickets 12,000-500,000 IU (0.3-12.5 mg) PO once daily Familial Hypophosphatemia 40,000-80,000 IU (1-2 mg) PO once daily with phosphate supplements; may be reduced after stage of growth is complete

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Colecalciferol is contraindicated in all diseases associated with hypercalcaemia. It is also contraindicated in patients with known hypersensitivity to Colecalciferol (or medicines of the same class) and any of the constituent excipients. Colecalciferol is contraindicated if there is evidence of vitamin D toxicity.

Precautions

People with the following conditions should exercise caution when considering taking vitamin D supplements: High blood Calcium or Phosphorus level Heart problems Kidney disease Vitamin D must be taken with adequate amounts of both Calcium and Magnesium supplementation. When Calcium level is low (due to insufficient vitamin D and calcium intake), the body activates the parathyroid gland, which produces PTH (parathyroid hormone). This hormone kick starts vitamin D hormone production and assists removal of Calcium from the bones to be used in more important functions such as neutralizing body acidity. Lactation: Drug is distributed into breast milk; use with caution

Pregnancy-Lactation

Interactions

Increased risk of hypercalcaemia if given with thiazide diuretics, calcium or phosphate. Antiepileptics (e.g. carbamazepine, phenobarbitone, phenytoin & primidone) may increase vitamin D requirements. Rifampicin & isoniazid may reduce efficacy of vitamin D. Corticosteroids may counteract the effect of vitamin D. Digoxin or any cardiac glycoside. Reduced absorption when taken with cholestyramine, colestipol, mineral oil, orlistat. Ketoconazole.

Adverse Effects

Side effects of Cholecalciferol (Vit. D3) : Generally all nutritional supplements are considered to be safe and well tolerable. However, few side-effects can generally occur including hypercalcaemia syndrome or Calcium intoxication (depending on the severity and duration of hypercalcaemia), occasional acute symptoms include anorexia, headache, dry mouth, nausea, vomiting, abdominal pain or stomach ache and constipation with the administration of Colecaciferol.

Mechanism of Action

Vitamin D3 is a fat-soluble sterol. It is necessary for the regulation and regulation of calcium and phosphate homoeostasis and bone mineralisation. Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. In addition to this it stimulates bone formation.

Note

DOLCIVIT 1000 1000 IU Capsules (Soft Gelatin) manufactured by GELTEC HEALTHCARE FZE. Its generic name is Cholecalciferol (Vit. D3). DOLCIVIT 1000 is availble in United Arab Emirates. Farmaco UAE drug index information on DOLCIVIT 1000 Capsules (Soft Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Cholecalciferol (Vit. D3) :

Solution / Oil
Devit-3 I.M Ampoule 300000 IU (8.25mg)/ml
DEVA HOLDING A.S
Capsules (Soft Gelatin)
Dferol 50 50000 IU
Pharmax Pharmaceuticals FZ LLC
Injection
Dibase "300,000 I.U./ml "
ABIOGEN PHARMA S.P.A
Solution (Oral)
Dibase " 25,000 I.U./2.5 mL"
ABIOGEN PHARMA S.P.A
Solution (Oral)
Dibase "50,000 I.U./2.5 mL"
ABIOGEN PHARMA S.P.A