Dramamine Tablets
Dimenhydrinate
50mg
Searle Pharmaceuticals
| Pack size | 6's |
|---|---|
| Dispensing mode | P |
| Source | UK |
| Agent | AL BAKER TRADING EST. |
| Retail Price | 2.50 AED |
Available as:
Indications
Dramamine Tablets is used for:
Prevention of Motion Sickness
Adult Dose
Prevention of Motion Sickness
50-100 mg PO/IV/IM q4-6hr PRN, 30 minutes before exposure to motion; not to exceed 400 mg/day
Child Dose
Prevention of Motion Sickness
General dose: 1.25 mg/kg or 37.5 mg/sq.meter IV/IM q6hr; not exceed 300 mg/day
2-6 years old: 12.5-25 mg PO q6-8hr; no more than 75 mg/day
6-12 years old: 12.5-25 mg PO q6-8hr; no more than 150 mg/day
>12 years old: Same as adult dosing
Renal Dose
Administration
IV Administration
50 mg in 10 mL NS over 2 min
Contra Indications
Documented hypersensitivity to dimenhydrinate or diphenhydramine
Lower respiratory disease, eg, asthma (controversial)
Preemies and neonates
Nursing women
Precautions
May impair ability to drive or operate heavy machinery
May mask early signs of ototoxicity if given concomitantly with ototoxic drugs (eg, aminoglycosides)
Patients with seizures, angle-closure glaucoma, enlargement of prostate gland, asthma, emphysema, acute hepatic insufficiency
Pregnancy-Lactation
Pregnancy Category: B
Lactation: Crosses into breast milk, discontinue drug or do not nurse
Interactions
Adverse Effects
Side effects of Dimenhydrinate :
requency Not Defined
Paradoxical CNS stimulation (children and occasionally in adults)
CNS depression
Drowsiness
Sedation ranging from mild drowsiness to deep sleep (most frequent)
Dizziness
Lassitude
Disturbed coordination
Muscular weakness
Restlessness, insomnia, tremors, euphoria, nervousness, delirium, palpitation, seizures is less common
Epigastric distress
Anorexia
Nausea
Vomiting
Diarrhea
Constipation
Cholestasis, hepatitis, hepatic failure, hepatic function abnormality, jaundice is rare
Eczema, pruritus, inflammation, papular rash, erythema on exposed skin may occur with topical formulation
Tachycardia, palpitation ECG changes (eg, widened QRS)
Arrhythmias (eg, extrasystole, heart block)
Hypotension
Hypertension
Dizziness, sedation, and hypotension may occur in geriatric patients
Dryness of mouth, nose, and throat
Dysuria
Urinary retention
Impotence
Vertigo
Visual disturbances
Blurred vision
Diplopia; tinnitus
Acute labyrinthitis
Insomnia
Tremors
Nervousness
Irritability
Facial dyskinesia
Tightness of the chest
Thickening of bronchial secretions
Wheezing
Nasal stuffiness
Sweating
Chills
Early menses
Toxic psychosis
Headache
Faintness
Paresthesia
Agranulocytosis
Hemolytic anemia
Leukopenia
Thrombocytopenia
Pancytopenia
Mechanism of Action
Ethanolamine H1 antagonist containing diphenhydramine and 8-chloro-theophylline; pharmacological effects principally result from diphenhydramine moiety, has CNS depressant, anticholinergic, antiemetic, antihistamine, and local anesthetic effects
Antiemetic action may result from inhibiting vestibular stimulation, and inhibiting acetylcholine
Note
Dramamine 50mg Tablets manufactured by Searle Pharmaceuticals. Its generic name is Dimenhydrinate. Dramamine is availble in United Arab Emirates.
Farmaco UAE drug index information on Dramamine Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.