Estracyt Capsules
Estramustine Phosphate (as phosphate sodium monohydrate )
140mg
PHARMACIA & UPJOHN AB.
Pack size | 100's Bottle |
---|---|
Dispensing mode | POM |
Source | SWEDEN |
Agent | AL RAZI PHARMACY |
Retail Price | 1038.00 AED |
Indications
Estracyt Capsules is used for:
For the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Estramustine Phosphate (as phosphate sodium monohydrate ) :
Mechanism of Action
Estramustine is a derivative of estradiol with a nitrogen mustard moiety. This gives it alkylating properties. In vivo, the nitrogen mustard component is active and can alklyate DNA and other cellular components (such as tubulin components) of rapidly dividing cells. This causes DNA strandbreaks or misscoding events. This leads to apoptosis and cell death. Also, due to the drugs estrogen component, it can bind more selectively to active estrogen receptors.
Note
Estracyt 140mg Capsules manufactured by PHARMACIA & UPJOHN AB.. Its generic name is Estramustine Phosphate (as phosphate sodium monohydrate ). Estracyt is availble in United Arab Emirates.
Farmaco UAE drug index information on Estracyt Capsules is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.