Eulexin Tablets
Flutamide
250mg
Schering-Plough Labo N.V.
| Pack size | 20's |
|---|---|
| Dispensing mode | POM |
| Source | BELGIUM |
| Agent | CITY MEDICAL STORE |
| Retail Price | 131.00 AED |
Available as:
Indications
Eulexin Tablets is used for:
Prostate cancer
Adult Dose
Oral
Palliative treatment of prostatic carcinoma
Adult: 250 mg tid preferably at least 3 days before gonadorelin analogue treatment.
Child Dose
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Precautions
Perform liver function tests before starting treatment and at regular intervals. Treatment is not recommended in patients whose ALT values exceed twice the upper limit of normal. Regular assessment of prostate specific antigen level may help to monitor disease progression. Advise patient against discontinuing drug on their own. Exercise caution in patients with cardiac disease.
Lactation: Excretion in milk unknown; not recommended
Pregnancy-Lactation
Pregnancy Category: D
Lactation: Excretion in milk unknown; not recommended
Interactions
Increased prothrombin time in patients on long-term warfarin treatment.
Adverse Effects
Side effects of Flutamide :
>10%
Hot flashes (61%), Decreased libido (36%), Impotence (31%), Diarrhea (12%), Nausea/vomiting (11%)
1-10%
Gynecomastia (9%), Anorexia (4%), Edema (4%), Leukopenia (3%), Rash (3%)
Frequency Not Defined
Hemolytic anemia, methemoglobinemia
Increased AST, ALT, bilirubin, BUN
Mechanism of Action
Flutamide is a nonsteroidal 'pure' antiandrogen which acts directly on the target tissues either by blocking androgen uptake or by inhibiting cytoplasmic and nuclear binding of androgen.
Note
Eulexin 250mg Tablets manufactured by Schering-Plough Labo N.V.. Its generic name is Flutamide. Eulexin is availble in United Arab Emirates.
Farmaco UAE drug index information on Eulexin Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.