Exoderil 1% Topical Solution

Naftifine Topical
10mg/ml
BIOCHEMIE GmbH
Pack size 10ml Bottle
Dispensing mode POM
Source AUSTRIA
AgentARABIAN ETHICALS CO.
Retail Price 12.00 AED

Indications

Exoderil 1% Topical Solution is used for: Skin fungal infections, treatment of interdigital tinea pedis, tinea cruris, and tinea corporis

Adult Dose

Topical/Cutaneous Skin fungal infections Adult: As hydrochloride: Apply sufficient amount of cream once daily or gel bid, morning and evening. Treatment duration: Tinea cruris and tinea corporis: 2-4 wk; tinea pedis: 4-6 wk; severe infections: May require prolonged treatment.

Child Dose

Renal Dose

Administration

Apply a thin layer to the affected areas plus half inch margin of healthy surrounding skin

Contra Indications

Hypersensitivity.

Precautions

Avoid contact with eyes, nose, mouth and other mucous membranes. Avoid use of occlusive dressings or wrappings. Discontinue use if irritation occurs. Pregnancy and lactation.

Pregnancy-Lactation

Pregnancy: There are no available data in pregnant women to inform the drug-associated risk for major birth defects and miscarriage; in animal reproduction studies, no adverse effects on embryofetal development were seen at oral doses administered during period of organogenesis up to 18 times maximum recommended human dose (MRHD) in pregnant rats or subcutaneous doses administered during period of organogenesis up to 2 times the MRHD in pregnant rats or 4 times the MRHD in pregnant rabbits Lactation: There is no information available on presence of drug in human milk, effects of drug on breastfed infant, or effects of drug on milk production; lack of clinical data during lactation precludes clear determination of risk of drug to infant during lactation; consider development and health benefits of breastfeeding along with mother’s clinical need for drug and any potential adverse effects on breastfed infant from drug or from underlying maternal condition

Interactions

Adverse Effects

Side effects of Naftifine Topical : Burning, stinging, dryness, redness, pruritus, local irritation, rash, skin tenderness.

Mechanism of Action

Naftifine is a synthetic allylamine antifungal that selectively inhibits the enzyme squalene monooxygenase resulting in reduced synthesis of the primary sterol, ergosterol, within the fungal membrane. It appears to have both fungicidal and fungistatic activity.

Note

Exoderil 1% 10mg/ml Topical Solution manufactured by BIOCHEMIE GmbH. Its generic name is Naftifine Topical. Exoderil 1% is availble in United Arab Emirates. Farmaco UAE drug index information on Exoderil 1% Topical Solution is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Naftifine Topical :