Fexon Tablets / Film-coated
Fexofenadine Hydrochloride
180mg
Neobiocon
| Pack size | 10's Blister |
|---|---|
| Dispensing mode | Ph-OM |
| Source | UAE |
| Agent | NEW MEDICAL CENTRE |
| Retail Price | 11.00 AED |
Available as:
Indications
Fexon Tablets / Film-coated is used for:
Seasonal Allergic rhinitis, Hay fever, Chronic Idiopathic Urticaria, Allergy
Adult Dose
Adults:
Seasonal Allergic Rhinitis/Chronic Idiopathic Urticaria
60 mg twice daily or 120 mg once daily or 180 mg once daily with water
Child Dose
Children:
Seasonal Allergic Rhinitis
<2 years: Use not recommended
2-12 years: 30 mg PO BID or 5 ml twice daily
>12 years: 60 mg PO BID OR 180 mg PO qDay
ODT
6-12 years: 30 mg PO BID
Chronic Idiopathic Urticaria
<6 months: Use not recommended
6 months-2 years: 15 mg PO BID or 2.5 ml twice daily
2-12 years: 30 mg PO BID
>12 years: 60 mg PO BID OR 180 mg PO qDay
ODT
6-12 years: 30 mg PO BID
Renal Dose
Renal impairment (CrCl <80 mL/min): 60 mg PO qDay initially
Administration
Should be taken on an empty stomach. Take before meals. Take with water. Do not take w/ fruit juice.
ODT: Allow to disintegrate on tongue, followed by swallowing with or without water;
Contra Indications
Hypersensitivity.
Precautions
Renal impairment. Pregnancy, lactation; children <6 yr.
Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)
Pregnancy-Lactation
Pregnancy category: C
Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)
Interactions
Co-admin with ketoconazole or erythromycin may increase plasma levels of fexofenadine. May increase adverse effects of other anticholinergics and CNS depressants. May increase arrhythmogenic effect of antipsychotic agents (phenothiazines); avoid concurrent usage. May reduce the efficacy of betahistine. Pramlintide may increase the anticholinergic effect of fexofenadine. Bioavailability may be increased by verapamil. Efficacy may be reduced by rifampin.
Adverse Effects
Side effects of Fexofenadine Hydrochloride :
>10%
Vomiting (6-12%)
1-10%
Headache (5-10%), Cough (4%), Diarrhea (3-4%), URTI (3%), Back pain (2-3%), Pyrexia (2%), Dysmenorrhea (2%), Dizziness (2%), Stomach discomfort (2%), Pain in extremity (2%), Somnolence (1-3%), Rhinorrhea (1-2%)
Mechanism of Action
Fexofenadine, an active metabolite of terfenadine, is a competitive peripheral histamine H1-receptor antagonist on effector cells in the GI tract, blood vessels and respiratory tract.
Note
Fexon 180mg Tablets / Film-coated manufactured by Neobiocon. Its generic name is Fexofenadine Hydrochloride. Fexon is availble in United Arab Emirates.
Farmaco UAE drug index information on Fexon Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.