Firazyr Solution for Injection
Icatibant
30mg/3ml
SHIRE PHARMACEUTICALS IRELAND LIMITED
| Pack size | 1 Prefilled Syringe (3 ml) + 1 Needle |
|---|---|
| Dispensing mode | POM |
| Source | IRELAND |
| Agent | CITY MEDICAL STORE |
| Retail Price | 9368.50 AED |
Indications
Firazyr Solution for Injection is used for:
Approved for use in acute attacks of hereditary angioedema (HAE). Investigated for use/treatment in angioedema, liver disease, and burns and burn infections.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Icatibant :
Mechanism of Action
Bradykinin is a peptide-based hormone that is formed locally in tissues in response to a trauma and acts to increases vessel permeability, dilates blood vessels and causes smooth muscle cells to contract. Bradykinin plays an important role in the mediation of pain as surplus bradykinin is partly responsible for producing signs of inflammation by activating bradykinin B2 receptors. In patients with HAE, they have an absent or dysfunctional C1-esterase inhibitor. This inhibitor is responsible for the production of bradykinin in which displacement of bradykinin from B2 receptors by icatibant has an inhibitory effect on the receptor for a relatively long time.
Note
Firazyr 30mg/3ml Solution for Injection manufactured by SHIRE PHARMACEUTICALS IRELAND LIMITED. Its generic name is Icatibant. Firazyr is availble in United Arab Emirates.
Farmaco UAE drug index information on Firazyr Solution for Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.