Flumen 50mg/2ml Injection
Fludarabine phosphate
50mg
MUSTAFA NEVZAT ILAC SANAYII A.S.
| Pack size | 1 Glass Vial |
|---|---|
| Dispensing mode | POM |
| Source | TURKEY |
| Agent | PHARMATRADE |
| Retail Price | 535.50 AED |
Indications
Flumen 50mg/2ml Injection is used for:
For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Fludarabine phosphate :
Mechanism of Action
Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite appears to act by inhibiting DNA polymerase alpha, ribonucleotide reductase and DNA primase, thus inhibiting DNA synthesis. The mechanism of action of this antimetabolite is not completely characterized and may be multi-faceted.
Note
Flumen 50mg/2ml 50mg Injection manufactured by MUSTAFA NEVZAT ILAC SANAYII A.S.. Its generic name is Fludarabine phosphate. Flumen 50mg/2ml is availble in United Arab Emirates.
Farmaco UAE drug index information on Flumen 50mg/2ml Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.