Haymine S.R Tablets
Chlorpheniramine maleate, Ephedrine Hcl
"10mg, 15mg"
PHARMAX LTD.
| Pack size | 10's Blister |
|---|---|
| Dispensing mode | POM |
| Source | UK |
| Agent | AL HAYAT PHARMACEUTICALS |
| Retail Price | 7.50 AED |
Available as:
Indications
Haymine S.R Tablets is used for:
PHENIRAMINE
Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria
EPHEDRINE
Ephedrine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia
Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria
EPHEDRINE
Ephedrine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Chlorpheniramine maleate, Ephedrine Hcl :
Mechanism of Action
PHENIRAMINE
Antihistamines such as pheniramine appear to compete with histamine for histamine h1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of h1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. Antihistamines suppress the histamine-induced wheal (swelling) and flare (vasodilation) response by blocking the binding of histamine to its receptors on nerves, vascular smooth muscle, glandular cells, endothelium, and mast cells. They effectively exert competitive antagonism of histamine for h1-receptors
EPHEDRINE
Ephedrine is a sympathomimetic amine - that is, its principal mechanism of action relies on its direct and indirect actions on the adrenergic receptor system, which is part of the sympathetic nervous system. Ephedrine increases post-synaptic noradrenergic receptor activity by (weakly) directly activating post-synaptic a-receptors and A-receptors, but the bulk of its effect comes from the pre-synaptic neuron being unable to distinguish between real adrenaline or noradrenaline from ephedrine. The ephedrine, mixed with noradrenaline, is transported through the noradrenaline reuptake complex and packaged (along with real noradrenaline) into vesicles that reside at the terminal button of a nerve cell. Ephedrine's action as an agonist at most major noradrenaline receptors and its ability to increase the release of both dopamine and to a lesser extent, serotonin by the same mechanism is presumed to have a major role in its mechanism of action
Antihistamines such as pheniramine appear to compete with histamine for histamine h1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of h1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. Antihistamines suppress the histamine-induced wheal (swelling) and flare (vasodilation) response by blocking the binding of histamine to its receptors on nerves, vascular smooth muscle, glandular cells, endothelium, and mast cells. They effectively exert competitive antagonism of histamine for h1-receptors
EPHEDRINE
Ephedrine is a sympathomimetic amine - that is, its principal mechanism of action relies on its direct and indirect actions on the adrenergic receptor system, which is part of the sympathetic nervous system. Ephedrine increases post-synaptic noradrenergic receptor activity by (weakly) directly activating post-synaptic a-receptors and A-receptors, but the bulk of its effect comes from the pre-synaptic neuron being unable to distinguish between real adrenaline or noradrenaline from ephedrine. The ephedrine, mixed with noradrenaline, is transported through the noradrenaline reuptake complex and packaged (along with real noradrenaline) into vesicles that reside at the terminal button of a nerve cell. Ephedrine's action as an agonist at most major noradrenaline receptors and its ability to increase the release of both dopamine and to a lesser extent, serotonin by the same mechanism is presumed to have a major role in its mechanism of action
Note
Haymine S.R "10mg, 15mg" Tablets manufactured by PHARMAX LTD.. Its generic name is Chlorpheniramine maleate, Ephedrine Hcl. Haymine S.R is availble in United Arab Emirates.
Farmaco UAE drug index information on Haymine S.R Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.