Helicap 37kbq Capsules (Hard Gelatin)

14C-Urea (as solution in ethanol 96%)

37kBq Units

KIBION AB

Pack size	10's Bottle
Dispensing mode	POM
Source	SWEDEN
Agent	GULF DRUG EST.
Retail Price	990.50 AED

Indications

Helicap 37kbq Capsules (Hard Gelatin) is used for: 14C-urea is intended for use in the detection of gastric urease as an aid in the diagnosis of Helicobacter pylori (H. pylori) infection in the human stomach. The test utilizes a liquid scintillation counter for the measurement of 14CO2 in breath samples.

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of 14C-Urea (as solution in ethanol 96%) :

Mechanism of Action

The urease enzyme is not present in mammalian cells, so the presence of urease in the stomach is evidence that bacteria are present. The presence of urease is not specific for H. pylori, but other bacteria are not usually found in the stomach. To detect H. pylori, urea labeled with 14C is swallowed by the patient. If gastric urease from H. pylori is present, urea is split to form CO2 and NH3 at the interface between the gastric epithelium and lumen and 14CO2 is absorbed into the blood and exhaled in the breath. Following ingestion of the capsule by a patient with H. pylori, 14CO2 excretion in the breath peaks between 10 and 15 minutes and declines thereafter with a biological half-life of about 15 minutes. Therefore, the detection of isotope-labelled carbon dioxide in exhaled breath indicates that urease is present in the stomach, and hence that H. pylori bacteria are present.

Note

Helicap 37kbq 37kBq Units Capsules (Hard Gelatin) manufactured by KIBION AB. Its generic name is 14C-Urea (as solution in ethanol 96%). Helicap 37kbq is availble in United Arab Emirates. Farmaco UAE drug index information on Helicap 37kbq Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.