Hemoclar Injection
Pentosan Polysulphate Sodium
NA
Sanofi-Clin Midy-Labaz
| Pack size | 1ml Ampoule x 10 |
|---|---|
| Dispensing mode | POM |
| Source | FRANCE |
| Agent | CITY MEDICAL STORE |
| Retail Price | 29.50 AED |
Available as:
Indications
Hemoclar Injection is used for:
Interstitial cystitis, Nocturia, Painful bladder syndrome, Dyspareunia
Adult Dose
Oral
Interstitial cystitis
Adult: 100 mg tid.
Child Dose
Renal Dose
Administration
Should be taken on an empty stomach. Take at least 1 hr before or 2 hr after meals.
Contra Indications
Patients who are haemorrhaging. Serious renal or hepatic impairment. Not to be given via IM inj.
Precautions
Patients with spleen disorders, hepatic or renal impairment. Monitor platelet counts during treatment. To discontinue treatment if thrombocytopenia occurs. Caution when used in patients with haemorrhagic blood disorders, thrombocytopenia, peptic ulcer disease, cerebrovascular disorders, bacterial endocarditis, severe hypertension or oesophageal varices. Recent surgery at sites where haemorrhage would be an especial risk. Safety not established in children <16 yr. Patients should be monitored every 3 mth; risks and benefits after 6 mth of treatment not known. Pregnancy; lactation.
Lactation: not known if excreted in breast milk, use caution
Pregnancy-Lactation
Pregnancy Category: B
Lactation: not known if excreted in breast milk, use caution
Interactions
Increased risk of bleeding when used with oral anticoagulants or drugs that affect platelet function. Concurrent admin with glyceryl trinitrate via IV route may reduce the efficacy of pentosan.
Adverse Effects
Side effects of Pentosan Polysulphate Sodium :
1-10%
Alopecia (4%), Diarrhea (4%), Nausea (4%), Headache (3%), Abdominal pain (2%), Indigestion (2%)
Mechanism of Action
Pentosan polysulfate sodium is a heparinoid with anticoagulant and fibrinolytic properties; it may also have hypolipidaemic and anti-inflammatory effects. It is used in thromboembolic disorders, although its anticoagulant effect is less than that of heparin. It is also used in the management of interstitial cystitis and has been tried in a number of other conditions, including variant Creutzfeldt-Jakob disease.
Note
Hemoclar NA Injection manufactured by Sanofi-Clin Midy-Labaz. Its generic name is Pentosan Polysulphate Sodium. Hemoclar is availble in United Arab Emirates.
Farmaco UAE drug index information on Hemoclar Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.