Histarhine Syrup
Pseudoephedrine + Triprolidine
"30mg, 1.25mg/5ml"
AMRIYA PHARMACEUTICAL INDUSTRIES COMPANY
| Pack size | 100ml Glass Bottle |
|---|---|
| Dispensing mode | POM |
| Source | EGYPT |
| Agent | THE POLARIZER FOR MEDICAL & CHEMICAL SUPPLIES |
| Retail Price | 4.00 AED |
Indications
Histarhine Syrup is used for:
Pneumonia, Pharyngitis, Allergic rhinitis, Upper respiratory tract, Dry cough, Tracheolaryngitis
Adult Dose
Oral
Allergic rhinitis, Cold and flu
Adult: Each tablet contains triprolidine HCl 2.5 mg and pseudoephedrine HCl 60 mg: 1 tablet 4-6 hrly, up to 4 times a day.
Child Dose
Oral
Allergic rhinitis, Cold and flu
Child > 12 yr: 1 tablet 4-6 hrly, up to 4 times a day.
Renal Dose
Administration
Contra Indications
Concurrent use or within 2 wk of stopping MAOIs. Severe hypertension or coronary artery disease.
Precautions
Severe hepatic impairment. Moderate to severe renal impairment. DM, hyperthyroidism, increased intraocular pressure, prostatic hypertrophy, hypertension, heart disease. May affect ability to drive or operate machinery. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Increased BP with other sympathomimetic agents (e.g. decongestants, TCA, appetite suppressants). Reduced hypotensive effects of methyldopa, ?- and ?-adrenergic blockers. Increased side effects (e.g. somnolence, agitation) with atomoxetine.
Potentially Fatal: Increased risk of hypertensive crisis with furazolidine, avoid concurrent use. Increased risk of hypertensive crisis with MAOIs; avoid concurrent use or within 2 wk after stopping MAOIs. Increased risk of psychosis with bromocriptine.
Adverse Effects
Side effects of Pseudoephedrine + Triprolidine :
Dry mouth, nose and throat; skin rashes, tachycardia, drowsiness, sleep disturbances, urinary retention. Rarely, hallucinations.
Mechanism of Action
Triprolidine hydrochloride is a potent competitive histamine H1-receptor antagonist with antimuscarinic and mild sedative properties. Pseudoephedrine, an alpha- and beta-adrenergic receptor agonist, mediates vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa.
Note
Histarhine "30mg, 1.25mg/5ml" Syrup manufactured by AMRIYA PHARMACEUTICAL INDUSTRIES COMPANY. Its generic name is Pseudoephedrine + Triprolidine. Histarhine is availble in United Arab Emirates.
Farmaco UAE drug index information on Histarhine Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Pseudoephedrine + Triprolidine :
Syrup
Unifed
"30mg, 1.25mg/5ml"
THE UNITED PHARMACEUTICAL MANUFACTURING CO. LTD.
Syrup (Alcohol-free)
Tripofed
30mg/1.25mg per 5ml
Kuwait Saudi Pharmaceutical Industries Co. (KSPICO)
Syrup
Trifed
"30mg, 1.25mg/5ml"
Al Hikma Pharmaceuticals
Tablets
Trifed
"60mg, 2.5mgTablet"
Al Hikma Pharmaceuticals
Tablets
Sedofan
"60mg, 2.5mg"
Julphar (Gulf Pharmaceutical Industries)