IMNOVID Capsules (Hard Gelatin)
Pomalidomide
4mg
CELGENE EUROPE BV.,
| Pack size | 21's |
|---|---|
| Dispensing mode | POM |
| Source | NETHERLANDS |
| Agent | CITY PHARMACY CO. |
| Retail Price | 50709.00 AED |
Available as:
Indications
IMNOVID Capsules (Hard Gelatin) is used for:
Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Pomalidomide :
Mechanism of Action
Promalidomide is an immunomodulatory agent with antineoplastic activity. It is shown to inhibit the proliferation and induce apoptosis of various tumour cells. Furthermore, promalidomide enhances T cell and natural killer (NK) cell-mediated immunity and inhibited the production of pro-inflammatory cytokines, like TNF-alpha or IL-6, by monocytes. The primary target of promalidomide is thought to be the protein cereblon. It binds to this target and inhibits ubiquitin ligase activity. It is also a transcriptional inhibitor of COX2.
Note
IMNOVID 4mg Capsules (Hard Gelatin) manufactured by CELGENE EUROPE BV.,. Its generic name is Pomalidomide. IMNOVID is availble in United Arab Emirates.
Farmaco UAE drug index information on IMNOVID Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.