INSULIN H Bio NPH Injection
Insulin - Isophane (Recombinant Human/Protamine sulfate)
100 IU/ml
SEDICO (SOUTH EGYPT DRUG INDUSTRIES COMPANY)
| Pack size | 10ml Vial |
|---|---|
| Dispensing mode | POM |
| Source | EGYPT |
| Agent | METROPOLITAN MEDICAL MARKETING |
| Retail Price | 36.50 AED |
Indications
INSULIN H Bio NPH Injection is used for:
Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Insulin - Isophane (Recombinant Human/Protamine sulfate) :
Mechanism of Action
The primary activity of insulin is the regulation of glucose metabolism. Insulin promotes glucose and amino acid uptake into muscle and adipose tissues, and other tissues except brain and liver. It also has an anabolic role in stimulating glycogen, fatty acid, and protein synthesis. Insulin inhibits gluconeogenesis in the liver. Insulin binds to the insulin receptor (ir), a heterotetrameric protein consisting of two extracellular alpha units and two transmembrane beta units. The binding of insulin to the alpha subunit of ir stimulates the tyrosine kinase activity intrinsic to the beta subunit of the receptor. The bound receptor is able to autophosphorylate and phosphorylate numerous intracellular substrates such as insulin receptor substrates (irs) proteins, cbl, aps, shc and gab 1. These activated proteins, in turn, lead to the activation of downstream signaling molecules including pi3 kinase and akt. Akt regulates the activity of glucose transporter 4 (glut4) and protein kinase c (pkc) which play a critical role in metabolism and catabolism
Note
INSULIN H Bio NPH 100 IU/ml Injection manufactured by SEDICO (SOUTH EGYPT DRUG INDUSTRIES COMPANY). Its generic name is Insulin - Isophane (Recombinant Human/Protamine sulfate). INSULIN H Bio NPH is availble in United Arab Emirates.
Farmaco UAE drug index information on INSULIN H Bio NPH Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.