Kolantyl Gel Suspension
Dicyclomine HCl, Magnesium oxide, Aluminium OH
Combination
MARION MERREL DOW PHARMACEUTICALS LIMITED
| Pack size | 12 oz |
|---|---|
| Dispensing mode | POM |
| Source | UK |
| Agent | CITY MEDICAL STORE |
| Retail Price | 12.50 AED |
Indications
Kolantyl Gel Suspension is used for:
DICYCLOMINE
For the treatment of functional bowel/irritable bowel syndrome including colicky abdominal pain; diverticulitis
MAGNESIUM OXIDE
Magnesium hydroxide is used as a laxative to relieve occasional constipation (irregularity) and as an antacid to relieve indigestion, sour stomach, and heartburn
ALUMINUM HYDROXIDE
For relief of heartburn and acid indigestion
For the treatment of functional bowel/irritable bowel syndrome including colicky abdominal pain; diverticulitis
MAGNESIUM OXIDE
Magnesium hydroxide is used as a laxative to relieve occasional constipation (irregularity) and as an antacid to relieve indigestion, sour stomach, and heartburn
ALUMINUM HYDROXIDE
For relief of heartburn and acid indigestion
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Dicyclomine HCl, Magnesium oxide, Aluminium OH :
Mechanism of Action
DICYCLOMINE
Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic)
MAGNESIUM OXIDE
The term "milk of magnesia" was first used to describe a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. Magnesium supplements have also been shown to reduce platelet aggregation by inhibiting in the influx of calcium, a crucial component of platelet aggregation
ALUMINUM HYDROXIDE
Aluminum hydroxide is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. Aluminum hydroxide is slowly solubilized in the stomach and reacts with hydrochloric acid to form aluminum chloride and water. It also inhibits the action of pepsin by increasing the ph and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (hco3-) and prostaglandins
Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic)
MAGNESIUM OXIDE
The term "milk of magnesia" was first used to describe a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. Magnesium supplements have also been shown to reduce platelet aggregation by inhibiting in the influx of calcium, a crucial component of platelet aggregation
ALUMINUM HYDROXIDE
Aluminum hydroxide is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. Aluminum hydroxide is slowly solubilized in the stomach and reacts with hydrochloric acid to form aluminum chloride and water. It also inhibits the action of pepsin by increasing the ph and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (hco3-) and prostaglandins
Note
Kolantyl Gel Combination Suspension manufactured by MARION MERREL DOW PHARMACEUTICALS LIMITED. Its generic name is Dicyclomine HCl, Magnesium oxide, Aluminium OH. Kolantyl Gel is availble in United Arab Emirates.
Farmaco UAE drug index information on Kolantyl Gel Suspension is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.