LOCOID CRELO 0.1% Cream (Emulsion)
Hydrocortisone 1% Topical
1mg/g
YAMANOUCHI EUROPE B.V.
| Pack size | 30g Plastic Bottle |
|---|---|
| Dispensing mode | POM |
| Source | NETHERLANDS |
| Agent | CITY MEDICAL STORE |
| Retail Price | 28.00 AED |
Available as:
Indications
LOCOID CRELO 0.1% Cream (Emulsion) is used for:
Corticosteroid-responsive dermatoses, Contact allergic dermatitis, Eczema - atopic; infantile; discoid; stasis, Seborrheic dermatitis, Skin irritations, itching and rashes, for example those caused by insect bites, minor thermal burns, sunburn, etc.
Adult Dose
Corticosteroid-responsive Dermatoses
Adult: Apply a thin film onto affected area 2-3 times daily.
Child Dose
Atopic Dermatitis
<3 months: Safety and efficacy not established
>3 months: Apply film to affected area q12hr
Corticosteroid-responsive Dermatoses
Apply q6-12hr
Dosing considerations
Limit to the minimum amount necessary for therapeutic efficacy
Renal Dose
Administration
Contra Indications
Viral/fungal infections, tubercular or syphilitic lesions, bacterial infections unless used in conjunction with appropriate chemotherapy.
Precautions
DM, elderly, patients on prolonged therapy. Pregnancy and lactation.
Lactation: Excretion in milk unknown; use with caution
Pregnancy-Lactation
Pregnancy
There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids; corticosteroids generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels; topical corticosteroids should be used during pregnancy only if potential benefits justify potential risk to fetus; should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time
Lactation
Not know whether topical administration could result in sufficient systemic absorption to produce detectable quantities in breast milk; systemically administered corticosteroids are secreted into breast milk in quantities not likely to have deleterious effect on infant; nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman
Interactions
Thiazides may enhance hyperglycaemia and hypokalaemia caused by corticosteroids. Increased incidence of peptic ulcer or GI bleeding with concurrent NSAIDs admin. Response to anticoagulants altered. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum conc of salicylates and antimuscarinic agents. Ethanol may enhance gastric mucosal irritation. Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone, barbiturates and rifampicin. Mutual inhibition of metabolism between ciclosporin and corticosteroids increase plasma conc of both drugs. Enhanced effect in women taking oestrogens or oral contraceptives.
Adverse Effects
Side effects of Hydrocortisone 1% Topical :
Skin atrophy, Striae, Acneform lesions, Perioral dermatitis, Folliculitis, Itching, Pigmentation changes, HPA suppression (with higher potency used >2 wk)
Mechanism of Action
Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.
Note
LOCOID CRELO 0.1% 1mg/g Cream (Emulsion) manufactured by YAMANOUCHI EUROPE B.V.. Its generic name is Hydrocortisone 1% Topical. LOCOID CRELO 0.1% is availble in United Arab Emirates.
Farmaco UAE drug index information on LOCOID CRELO 0.1% Cream (Emulsion) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
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