Locoid Lipo 0.1% Cream

Hydrocortisone 1% Topical
1mg/g
ASTELLASE PHARMA EUROPE B.V.
Pack size 30g Tube
Dispensing mode POM
Source NETHERLANDS
AgentCITY MEDICAL STORE
Retail Price 28.00 AED

Indications

Locoid Lipo 0.1% Cream is used for: Corticosteroid-responsive dermatoses, Contact allergic dermatitis, Eczema - atopic; infantile; discoid; stasis, Seborrheic dermatitis, Skin irritations, itching and rashes, for example those caused by insect bites, minor thermal burns, sunburn, etc.

Adult Dose

Corticosteroid-responsive Dermatoses Adult: Apply a thin film onto affected area 2-3 times daily.

Child Dose

Atopic Dermatitis <3 months: Safety and efficacy not established >3 months: Apply film to affected area q12hr Corticosteroid-responsive Dermatoses Apply q6-12hr Dosing considerations Limit to the minimum amount necessary for therapeutic efficacy

Renal Dose

Administration

Contra Indications

Viral/fungal infections, tubercular or syphilitic lesions, bacterial infections unless used in conjunction with appropriate chemotherapy.

Precautions

DM, elderly, patients on prolonged therapy. Pregnancy and lactation. Lactation: Excretion in milk unknown; use with caution

Pregnancy-Lactation

Pregnancy There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids; corticosteroids generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels; topical corticosteroids should be used during pregnancy only if potential benefits justify potential risk to fetus; should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time Lactation Not know whether topical administration could result in sufficient systemic absorption to produce detectable quantities in breast milk; systemically administered corticosteroids are secreted into breast milk in quantities not likely to have deleterious effect on infant; nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman

Interactions

Thiazides may enhance hyperglycaemia and hypokalaemia caused by corticosteroids. Increased incidence of peptic ulcer or GI bleeding with concurrent NSAIDs admin. Response to anticoagulants altered. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum conc of salicylates and antimuscarinic agents. Ethanol may enhance gastric mucosal irritation. Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone, barbiturates and rifampicin. Mutual inhibition of metabolism between ciclosporin and corticosteroids increase plasma conc of both drugs. Enhanced effect in women taking oestrogens or oral contraceptives.

Adverse Effects

Side effects of Hydrocortisone 1% Topical : Skin atrophy, Striae, Acneform lesions, Perioral dermatitis, Folliculitis, Itching, Pigmentation changes, HPA suppression (with higher potency used >2 wk)

Mechanism of Action

Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.

Note

Locoid Lipo 0.1% 1mg/g Cream manufactured by ASTELLASE PHARMA EUROPE B.V.. Its generic name is Hydrocortisone 1% Topical. Locoid Lipo 0.1% is availble in United Arab Emirates. Farmaco UAE drug index information on Locoid Lipo 0.1% Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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