Ludiomil Tablets
Maprotiline Hydrochloride
75mg
Novartis Pharma AG
| Pack size | 20's (10's Blister x 2) |
|---|---|
| Dispensing mode | POM |
| Source | SWITZERLAND |
| Agent | CITY MEDICAL STORE |
| Retail Price | 72.50 AED |
Available as:
Indications
Ludiomil Tablets is used for:
Depression
Adult Dose
Oral
Depression
Adult: As hydrochloride: 25-75 mg daily in 3 divided doses, gradually increased in 25 mg increments at 1-2 wk intervals to 150 mg/day if necessary. Up to 225 mg/day in severely depressed patients.
Elderly: Initial: 25 mg daily. May increase slowly according to response to 50-75 mg daily if needed.
Child Dose
Safety and effecay not established
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Preexisting CV insufficiency; epilepsy or lowered seizure threshold.
Precautions
Urinary retention, prostatic hyperplasia, chronic constipation, untreated angle-closure glaucoma; hyperthyroidism; risk of suicide; may precipitate mania or psychotic symptoms; withdraw gradually; may impair ability to operate machinery. Pregnancy and lactation; elderly.
Lactation: avoid during breastfeeding
Pregnancy-Lactation
Pregnancy Category: B
Lactation: avoid during breastfeeding
Interactions
MAOIs. Increase in sedative effect with alcohol. Increased effect of antidiabetics. Maprotiline concentrations and toxicity increased by propranolol, risperidone. Risk of seizures increased with phenothiazines.
Adverse Effects
Side effects of Maprotiline Hydrochloride :
Common
Fatigue, Sedation, Lethargy, Weakness, Constipation, Dry mouth, Blurred vision
Less Common
Agitation, Anxiety, Headache, Insomnia, Nausea, Vomiting, Sweating
Infrequent
Orthostatic hypotension, ECG changes, tachycardia
Confusion, EPS, dizziness, paresthesia, tinnitus
Rash, Incr LFTs, Sexual dysfunction
Rare
Seizure, Agranulocytosis, Thrombocytopenia, Eosinophilia, Leukopenia, SIADH
Potentially Fatal: Seizures
Mechanism of Action
Maprotiline is a tetracyclic antidepressant pharmacologically similar to the tricyclic antidepressants. It's antidepressant effects appear to be due principally to inhibition of the re-uptake of noradrenaline at the neuronal membrane.
Note
Ludiomil 75mg Tablets manufactured by Novartis Pharma AG. Its generic name is Maprotiline Hydrochloride. Ludiomil is availble in United Arab Emirates.
Farmaco UAE drug index information on Ludiomil Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.