MEDIVITAN IV Injection
Pyridoxine hydrochloride, Cyanocobalamin, Folic acid
"5mg, 1mg/4ml, 1.1mg/ml"
MEDICE ARZNEIMITTEL PUTTER GmbH & CO. KG.
| Pack size | 8 + 8 Ampoules (Injection-I: 4ml Ampoule x 8 + Injection-II: 1ml Ampoule x 8) |
|---|---|
| Dispensing mode | POM |
| Source | GERMANY |
| Agent | PHARMALINK |
| Retail Price | 104.50 AED |
Indications
MEDIVITAN IV Injection is used for:
PYRIDOXINE
For the treatment of vitamin b6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy
CYANOCOBALAMIN
For treatment of pernicious anemia (due to lack of or inhibition of intrinsic factor) and for prevention and treatment of vitamin b 12 deficiency
FOLIC ACID
For treatment of folic acid deficiency, megaloblastic anemia and in anemias of nutritional supplements, pregnancy, infancy, or childhood
For the treatment of vitamin b6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy
CYANOCOBALAMIN
For treatment of pernicious anemia (due to lack of or inhibition of intrinsic factor) and for prevention and treatment of vitamin b 12 deficiency
FOLIC ACID
For treatment of folic acid deficiency, megaloblastic anemia and in anemias of nutritional supplements, pregnancy, infancy, or childhood
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Pyridoxine hydrochloride, Cyanocobalamin, Folic acid :
Mechanism of Action
PYRIDOXINE
Vitamin b6 is the collective term for a group of three related compounds, pyridoxine (pn), pyridoxal (pl) and pyridoxamine (pm), and their phosphorylated derivatives, pyridoxine 5'-phosphate (pnp), pyridoxal 5'-phosphate (plp) and pyridoxamine 5'-phosphate (pmp). Although all six of these compounds should technically be referred to as vitamin b6, the term vitamin b6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin b6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (gaba)
CYANOCOBALAMIN
Vitamin b12 is used in the body in two forms: methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for dna methylation. 5-deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts l-methylmalonyl-coa to succinyl-coa. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl coa is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells
FOLIC ACID
Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate trna, and generate and use formate. Using vitamin b12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase
Vitamin b6 is the collective term for a group of three related compounds, pyridoxine (pn), pyridoxal (pl) and pyridoxamine (pm), and their phosphorylated derivatives, pyridoxine 5'-phosphate (pnp), pyridoxal 5'-phosphate (plp) and pyridoxamine 5'-phosphate (pmp). Although all six of these compounds should technically be referred to as vitamin b6, the term vitamin b6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin b6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (gaba)
CYANOCOBALAMIN
Vitamin b12 is used in the body in two forms: methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for dna methylation. 5-deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts l-methylmalonyl-coa to succinyl-coa. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl coa is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells
FOLIC ACID
Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate trna, and generate and use formate. Using vitamin b12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase
Note
MEDIVITAN IV "5mg, 1mg/4ml, 1.1mg/ml" Injection manufactured by MEDICE ARZNEIMITTEL PUTTER GmbH & CO. KG.. Its generic name is Pyridoxine hydrochloride, Cyanocobalamin, Folic acid. MEDIVITAN IV is availble in United Arab Emirates.
Farmaco UAE drug index information on MEDIVITAN IV Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.