Mikostat Ointment
Nystatin
100000 IU/g
Julphar (Gulf Pharmaceutical Industries)
| Pack size | 15g Tube |
|---|---|
| Dispensing mode | POM |
| Source | UAE |
| Agent | JULPHAR |
| Retail Price | 6.50 AED |
Available as:
Indications
Mikostat Ointment is used for:
Fungal infections, Oropharyngeal candidiasis, Intestinal candidiasis, Vaginal candidiasis
Adult Dose
Oral
Oral candidiasis
Adult: As oral susp or drop : 100,000-600,000 U (1-6 ml drop) into the mouth 4 times daily. Keep in contact w/ affected area as long as possible.
Continue for 48 hr after clinical cure to prevent relapse.
Intestinal candidiasis
Adult: As tab or oral susp/drop: 500,000 or 1,000,000 U 3-4 times daily.
Prophylaxis: 1,000,000 U daily.
Vaginal
Vulvovaginal candidiasis
Adult: insert 1 vaginal tablet into vagina daily at bedtime for 14 days or longer.
Child Dose
As oral susp or drop
Infants: PO: 2 mL/dose, children 4–6 mL/dose, to coat oral mucosa q6h
As tab
Child: PO: 3–6 tabs/day tid
For prophylaxis of oral candidiasis in the newborn the suggested dose is
1 ml (100,000 U) once daily. Administration should be continued for 48 hours after clinical cure to prevent relapse.
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity.
Precautions
Immunocompromised patients. Childn. Pregnancy and lactation. Patient Counselling May damage latex contraceptives (vag).
Lactation: Not known if excreted in breast milk; use caution
Pregnancy-Lactation
Pregnancy category: C, ROUTE(S) : Mouth/Throat / PO
Pregnancy Category: A, ROUTE(S) : Vaginal
Interactions
Adverse Effects
Side effects of Nystatin :
Nausea, vomiting, diarrhoea, GI upset, oral irritation and sensitisation. Rarely, rash, urticaria, Stevens-Johnson syndrome, tachycardia, bronchospasm, facial swelling, nonspecific myalgia
Vaginal tablet: May damage latex contraceptives (e.g. diaphragms, condoms), additional contraceptive measures should be taken. Localized sensitization.
Mechanism of Action
Nystatin, a polyene antifungal, binds to ergosterol in the fungal cell membrane. This binding affects the cell wall permeability allowing leakage of cellular contents.
Note
Mikostat 100000 IU/g Ointment manufactured by Julphar (Gulf Pharmaceutical Industries). Its generic name is Nystatin. Mikostat is availble in United Arab Emirates.
Farmaco UAE drug index information on Mikostat Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Nystatin :
Cream
Mikostat
100000 IU/g
Julphar (Gulf Pharmaceutical Industries)
Suspension
MIKOSTAT
"100,000 IU/ml"
Julphar (Gulf Pharmaceutical Industries)
Suspension
MYCOSAT
100000 IU/ml
Amman Pharmaceutical Industries Co. Ltd.
Vaginal Tablets
NILSTAT
"100,000 IU"
LEDERLE PHARMACEUTICALS (CYANAMIDE GmbH)
Cream
NILSTAT
"100,000 IU/g"
LEDERLE PHARMACEUTICALS (CYANAMIDE GmbH)