Neo-Mercazole Tablets
Carbimazole
5mg
AMDIPHARM LTD
| Pack size | 100's Bottle |
|---|---|
| Dispensing mode | POM |
| Source | IRELAND |
| Agent | PHARMATRADE |
| Retail Price | 21.00 AED |
Indications
Neo-Mercazole Tablets is used for:
Grave's disease, Hyperthyroidism, Diabetic nephropathy, Preparation for thyroidectomy
Adult Dose
Oral
Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy
Adult: Initially, 20-60 mg daily as a single or divided dose, reduced gradually once euthyroidism is achieved. Maintenance: 5-15 mg daily for at least 1 yr or 18 mth.
Hepatic impairment: Severe: Contraindicated.
Child Dose
Oral
Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy
Child: 3-17 yr Initially, 15 mg daily, adjusted according to response.
Renal Dose
Administration
May be taken with or without food. Take consistently w/ or w/o meals.
Contra Indications
Hyperthyroidism due to nodular goitre.
Precautions
Liver diseases, pregnancy, lactation.
Pregnancy-Lactation
Interactions
Increased serum levels of theophylline or may develop toxicity. May enhance the effect of anticoagulants.
Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.
Adverse Effects
Side effects of Carbimazole :
Mild leucopaenia, sore throat, mouth ulcers, fever, bruising, malaise; rarely cholestatic jaundice; nephrotic syndrome. Nausea, loss of taste, headache, arthralgia, alopoecia.
Potentially Fatal: Agranulocytosis, aplastic anaemia, hypoprothrombinaemia, neutropaenia; hypothyroidism and goitre.
Mechanism of Action
Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.
Note
Neo-Mercazole 5mg Tablets manufactured by AMDIPHARM LTD. Its generic name is Carbimazole. Neo-Mercazole is availble in United Arab Emirates.
Farmaco UAE drug index information on Neo-Mercazole Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.