Netromycine 150mg/1.5ml Injection

Netilmicin (as sulphate)
100mg/ml
Schering-Plough Labo N.V.
Pack size 1.5ml Vial
Dispensing mode POM
Source BELGIUM
AgentCITY MEDICAL STORE
Retail Price 42.00 AED

Indications

Netromycine 150mg/1.5ml Injection is used for: For the treatment of bacteremia, septicaemia, respiratory tract infections, skin and soft-tissue infection, burns, wounds, and peri-operative infections caused by susceptible strains.

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Netilmicin (as sulphate) :

Mechanism of Action

Aminoglycosides like netilmicin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically netilmicin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes, leaving the bacterium unable to synthesize proteins vital to its growth.

Note

Netromycine 150mg/1.5ml 100mg/ml Injection manufactured by Schering-Plough Labo N.V.. Its generic name is Netilmicin (as sulphate). Netromycine 150mg/1.5ml is availble in United Arab Emirates. Farmaco UAE drug index information on Netromycine 150mg/1.5ml Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Netilmicin (as sulphate) :