Nexavar Tablets / Film-coated
Sorafenib (as tosylate, micronized)
200mg
BAYER HEALTHCARE AG
| Pack size | 60's (10's Blister x 6) |
|---|---|
| Dispensing mode | POM |
| Source | GERMANY |
| Agent | ALPHAMED CO. (AUH) LTD. |
| Retail Price | 11450.50 AED |
Indications
Nexavar Tablets / Film-coated is used for:
Sorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Sorafenib (as tosylate, micronized) :
Mechanism of Action
Sorafenib interacts with multiple intracellular (CRAF, BRAF and mutant BRAF) and cell surface kinases (KIT, FLT-3, VEGFR-2, VEGFR-3, and PDGFR-ß). Several of these kinases are thought to be involved in angiogenesis, thus sorafenib reduces blood flow to the tumor. Sorafenib is unique in targeting the Raf/Mek/Erk pathway. By inhibiting these kinases, genetic transcription involving cell proliferation and angiogenesis is inhibited.
Note
Nexavar 200mg Tablets / Film-coated manufactured by BAYER HEALTHCARE AG. Its generic name is Sorafenib (as tosylate, micronized). Nexavar is availble in United Arab Emirates.
Farmaco UAE drug index information on Nexavar Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.