Omnaris Nasal Spray / Pump
Ciclesonide
50mcg/Dose
NYCOMED CANADA INC.
| Pack size | 120 Puffs Nasal Spray |
|---|---|
| Dispensing mode | POM |
| Source | CANADA |
| Agent | ALPHAMED DRUG STORE |
| Retail Price | 82.00 AED |
Indications
Omnaris Nasal Spray / Pump is used for:
Asthma, seasonal allergic rhinitis, perennial allergic rhinitis
Adult Dose
Inhalation
Asthma
Adult: Usual dose 160 mcg once daily, preferably in the evening from a metered-dose inhaler; reduced to 80 mcg once daily for maintenance.
May increase to 160 mcg twice daily
Nasal Spray:
1 spray (50 micrograms/spray) in each nostril once a day. The maximum total daily dosage should not exceed 2 sprays in each nostril (200 micrograms/day).
Child Dose
Inhalation
Asthma
Child: >12 yr: Usual dose 160 mcg once daily, preferably in the evening from a metered-dose inhaler; reduced to 80 mcg once daily for maintenance.
May increase to 160 mcg twice daily
Nasal Spray:
1 spray (50 micrograms/spray) in each nostril once a day. The maximum total daily dosage should not exceed 2 sprays in each nostril (200 micrograms/day).
Renal Dose
Administration
Gently shake and prime nasal spray by actuating 3 times before using for the first time or when not in use for 4 consecutive days
Contra Indications
Not for status asthmaticus or severe acute asthma where intensive measures are needed. Ciclesonide nasal spray is contraindicated in patients with a hypersensitivity to any of its ingredients.
Precautions
Active or quiescent pulmonary TB, fungal, viral or bacterial infections, unless adequately treated. Severe hepatic impairment. Monitor height of children and adolescents on long term treatment with inhaled corticosteroids; reduce dose if growth is slow. Pregnancy, lactation.
Ciclesonide nasal spray should be used with caution in patients with active or quiescent tuberculosis infection of the respiratory tract or in patients with untreated fungal, bacterial or systemic viral infections or ocular herpes simplex. Rare instances of nasal septal perforation, cataract, and glaucoma have been reported following intranasal application. Development of localized infections of the nose and pharynx with Candida albcans has rarely occurred. Although systemic effects have been minimal with recommended doses of Ciclesonide nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of Ciclesonide nasal spray should be avoided.
Lactation: Not known if excreted in breast milk, use caution
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Not known if excreted in breast milk, use caution
Interactions
Increased ciclesonide concentrations with concomitant ketoconazole, itraconazole, ritonavir, nelfinavir or other potent CYP3A4 inhibitors.
Adverse Effects
Side effects of Ciclesonide :
Inhalation
>10%
Headache (11%), Nasopharyngitis (11%)
1-10%
Epistaxis (4.9%), Ear pain (2.2%), Facial edema (3%), Urticaria (3%), Oral candidiasis (3%), Back pain (3%), Extremety pain (3%), Conjunctivitis (3%), Upper respiratory infection (9%), Gastroenteritis (3%), Sinusitis (3%)
Nasal spray
1-10%
Headache (3.1-6.6%), Epistaxis (2.9-6%), Nasopharyngitis (3.7%), Nasal discomfort (3.2%), Ear pain (2.2%)
Mechanism of Action
Ciclesonide, an inhaled corticosteriod, is converted by esterases in the lungs to the active metabolite, desisobutyryl-ciclesonide, which has anti-inflammatory activity.
Note
Omnaris 50mcg/Dose Nasal Spray / Pump manufactured by NYCOMED CANADA INC.. Its generic name is Ciclesonide. Omnaris is availble in United Arab Emirates.
Farmaco UAE drug index information on Omnaris Nasal Spray / Pump is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.