Peyona Infusion and Oral Solution
Caffeine Citrate
20mg/ml
Chiesi Farmaceutici S.p.A.
| Pack size | 10's (5's x 2) Glass Ampoules |
|---|---|
| Dispensing mode | POM |
| Source | ITALY |
| Agent | New Country Healthcare L.L.C. |
| Retail Price | 1040.00 AED |
Indications
Peyona Infusion and Oral Solution is used for:
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Caffeine Citrate :
Mechanism of Action
Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. This action was previously believed to be due primarily to increased intracellular cyclic 3′,5′-adenosine monophosphate (cyclic AMP) following inhibition of phosphodiesterase, the enzyme that degrades cyclic AMP. It is now thought that xanthines such as caffeine act as antagonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced "pounding" of the heart upon caffeine intake.
Note
Peyona 20mg/ml Infusion and Oral Solution manufactured by Chiesi Farmaceutici S.p.A.. Its generic name is Caffeine Citrate. Peyona is availble in United Arab Emirates.
Farmaco UAE drug index information on Peyona Infusion and Oral Solution is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.