Physiotens Tablets / Film-coated
Moxonidine
0.4mg
Abbott Laboratories S.A
| Pack size | 28's (14's Blister x 2) |
|---|---|
| Dispensing mode | POM |
| Source | UAE |
| Agent | ALPHAMED CO. (AUH) LTD. |
| Retail Price | 72.00 AED |
Available as:
Indications
Physiotens Tablets / Film-coated is used for:
Hypertension
Adult Dose
Oral
Hypertension
Adult: 200 mcg once daily, increase if necessary after 3 wk to 400 mcg daily as single or in 2 divided doses. If necessary, after a further 3 wk, increase to 600 mcg daily in 2 divided doses. Max: 600 mcg daily.
Child Dose
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
30-60 Single dose should not exceed 200 mcg. Max daily dose 400 mcg.
<30 Avoid
Administration
May be taken with or without food.
Contra Indications
Conduction disorders; bradycardia; severe arrhythmias; severe heart failure; severe ischaemic heart disease; history of angioedema; severe liver or renal impairment; Raynaud's syndrome; intermittent claudication; epilepsy; depression; Parkinson's disease; glaucoma. Pregnancy and lactation.
Precautions
Renal impairment; avoid abrupt withdrawal (if concomitant treatment with ?-blocker has to be stopped, discontinue ?-blocker first, then moxonidine after few days).
Pregnancy-Lactation
Interactions
Additive effects with other antihypertensives; may increase sedative effects of benzodiazepines. Effects may be antagonised by TCAs.
Adverse Effects
Side effects of Moxonidine :
Dry mouth; headache; fatigue; dizziness; nausea; sleep disturbances; asthenia; vasodilatation; skin reactions; constipation; depression; anxiety; anorexia; parotid pain; vivid dreams; impotence and loss of libido; urinary retention or incontinence; slight orthostastic hypotension; fluid retention.
Mechanism of Action
Moxonidine is a centrally-acting antihypertensive. It acts in the brainstem through stimulation of central imidazoline receptors to reduce sympathetic tone. Moxonidine also has a low affinity for alpha2-adrenoceptors.
Note
Physiotens 0.4mg Tablets / Film-coated manufactured by Abbott Laboratories S.A. Its generic name is Moxonidine. Physiotens is availble in United Arab Emirates.
Farmaco UAE drug index information on Physiotens Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.